Mefenamic acid and Hepatocellular damage - a phase IV clinical study of FDA data

Summary:

Hepatocellular damage is reported as a side effect among people who take Mefenamic acid (mefenamic acid), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Norvasc, and have Pain.

The phase IV clinical study analyzes which people have Hepatocellular damage when taking Mefenamic acid. It is created by eHealthMe based on reports of 4,738 people who have side effects when taking Mefenamic acid from the FDA, and is updated regularly.

What is Mefenamic acid?

Mefenamic acid has active ingredients of mefenamic acid. It is often used in painful menstrual periods. eHealthMe is studying from 4,844 Mefenamic acid users. Check the latest studies of Mefenamic acid.

What is Hepatocellular damage?

Hepatocellular damage (liver damage) is found to be associated with 511 drugs and 610 conditions by eHealthMe. Check the latest studies of Hepatocellular damage.

On Jul, 18, 2026

4,738 people reported to have side effects when taking Mefenamic acid.
Among them, 12 people (0.25%) have Hepatocellular damage.

Could Mefenamic acid cause Hepatocellular damage?

Among these 12 people:

How long have people been on Mefenamic acid when they have Hepatocellular damage? *

What is the gender of people who have Hepatocellular damage when taking Mefenamic acid? *

female: 50 %
male: 50 %

What is the age of people who have Hepatocellular damage when taking Mefenamic acid? *

What are other drugs people take besides Mefenamic acid? *

Norvasc: 3 people, 25.00%
Viagra: 2 people, 16.67%
Tamiflu: 2 people, 16.67%
Tagamet: 2 people, 16.67%
Vancomycin Hydrochloride: 2 people, 16.67%
Biaxin: 2 people, 16.67%
Cefuroxime Axetil: 2 people, 16.67%
Cefaclor: 1 person, 8.33%
Amoxicillin: 1 person, 8.33%
Augmentin '125': 1 person, 8.33%

What are other side effects people have besides Hepatocellular damage? *

Malaise (a feeling of general discomfort or uneasiness): 4 people, 33.33%
Nausea (feeling of having an urge to vomit): 4 people, 33.33%
Fever: 3 people, 25.00%
Liver Function Tests Nos Abnormal: 3 people, 25.00%
Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 2 people, 16.67%
Anorexia (eating disorder characterized by immoderate food restriction and irrational fear of gaining weight): 2 people, 16.67%
Thrombocytopenia (decrease of platelets in blood): 2 people, 16.67%
Urine Discoloration: 2 people, 16.67%
Rashes (redness): 2 people, 16.67%
Muscle Rigidity (muscle stiffness): 1 person, 8.33%

What are the existing conditions these people have? *

Pain: 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Mefenamic acid and have Hepatocellular damage?

- Check whether Hepatocellular damage is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Mefenamic acid:

Mefenamic acid (4,844 reports)

Browse all side effects of Mefenamic acid:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hepatocellular damage:

Hepatocellular damage (511 drugs)

Browse all the conditions that are associated with Hepatocellular damage:

Hepatocellular damage (610 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on mefenamic acid (the active ingredients of Mefenamic acid) and Mefenamic acid (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.