Mefloquine and Weakness - a phase IV clinical study of FDA data

Summary:

Weakness is reported as a side effect among people who take Mefloquine (mefloquine hydrochloride), especially for people who are female, 40-49 old, have been taking the drug for 1 - 6 months also take Prednisone, and have Systemic lupus erythematosus.

The phase IV clinical study analyzes which people have Weakness when taking Mefloquine. It is created by eHealthMe based on reports of 899 people who have side effects when taking Mefloquine from the FDA, and is updated regularly.

What is Mefloquine?

Mefloquine has active ingredients of mefloquine hydrochloride. It is often used in malaria. eHealthMe is studying from 991 Mefloquine users. Check the latest studies of Mefloquine.

What is Weakness?

Weakness is found to be associated with 3,640 drugs and 6,612 conditions by eHealthMe. Check the latest studies of Weakness.



On May, 13, 2026

899 people reported to have side effects when taking Mefloquine.
Among them, 58 people (6.45%) have Weakness.

Could Mefloquine cause Weakness?

Among these 58 people:

How long have people been on Mefloquine when they have Weakness? *

  • < 1 month: 38.46 %
  • 1 - 6 months: 46.15 %
  • 6 - 12 months: 7.69 %
  • 1 - 2 years: 7.69 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Weakness when taking Mefloquine? *

  • female: 54.17 %
  • male: 45.83 %

What is the age of people who have Weakness when taking Mefloquine? *

  • 0-1: 0.0 %
  • 2-9: 4.55 %
  • 10-19: 2.27 %
  • 20-29: 11.36 %
  • 30-39: 18.18 %
  • 40-49: 27.27 %
  • 50-59: 18.18 %
  • 60+: 18.18 %

What are other drugs people take besides Mefloquine? *

  1. Acetaminophen: 10 people, 17.24%
  2. Prednisone: 10 people, 17.24%
  3. Methylprednisolone: 9 people, 15.52%
  4. Ramipril: 8 people, 13.79%
  5. Dapsone: 8 people, 13.79%
  6. Cyclophosphamide: 8 people, 13.79%
  7. Benlysta: 8 people, 13.79%
  8. Azathioprine: 8 people, 13.79%
  9. Diphenhydramine Hydrochloride: 8 people, 13.79%
  10. Levothyroxine Sodium: 7 people, 12.07%

What are other side effects people have besides Weakness? *

  1. Stress And Anxiety: 14 people, 24.14%
  2. Fatigue (feeling of tiredness): 13 people, 22.41%
  3. Nausea (feeling of having an urge to vomit): 13 people, 22.41%
  4. Dizziness: 12 people, 20.69%
  5. Headache (pain in head): 10 people, 17.24%
  6. Pain In Extremity: 10 people, 17.24%
  7. Progressive Multifocal Leukoencephalopathy (rapidly progressive neuromuscular disease caused by opportunistic infection of brain cells): 9 people, 15.52%
  8. Drug Ineffective: 8 people, 13.79%
  9. Type 1 Diabetes: 8 people, 13.79%
  10. Insomnia (sleeplessness): 7 people, 12.07%

What are the existing conditions these people have? *

  1. Systemic Lupus Erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue): 8 people, 13.79%
  2. Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 4 people, 6.90%
  3. Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 3 people, 5.17%
  4. Primary Myelofibrosis (primary disorder of the bone marrow): 2 people, 3.45%
  5. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 2 people, 3.45%
  6. Type 1 Diabetes: 1 person, 1.72%
  7. Rickets (softening of bones): 1 person, 1.72%
  8. Progressive Multifocal Leukoencephalopathy (rapidly progressive neuromuscular disease caused by opportunistic infection of brain cells): 1 person, 1.72%
  9. Pain: 1 person, 1.72%
  10. Osteoporosis Post-Menopausal (weak bone with possibility to break after stopped menstrual cycles): 1 person, 1.72%

* Approximation only. Some reports may have incomplete information.

Do you take Mefloquine and have Weakness?

- Check whether Weakness is associated with a drug or a condition
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Mefloquine:

Weakness treatments and more:

How severe was Weakness and when was it recovered:

Expand to all the drugs that have ingredients of mefloquine hydrochloride:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Mefloquine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Weakness:

Browse all the conditions that are associated with Weakness:


How the study uses the data?

The study uses data from the FDA. It is based on mefloquine hydrochloride (the active ingredients of Mefloquine) and Mefloquine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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