Mektovi and Hot flush - a phase IV clinical study of FDA data

Summary:

Hot flush is reported as a side effect among people who take Mektovi (binimetinib), especially for people who are 60+ old, have been taking the drug for 1 - 6 months also take Braftovi, and have Breast cancer female.

The phase IV clinical study analyzes which people have Hot flush when taking Mektovi. It is created by eHealthMe based on reports of 6,177 people who have side effects when taking Mektovi from the FDA, and is updated regularly.

What is Mektovi?

Mektovi has active ingredients of binimetinib. eHealthMe is studying from 6,179 Mektovi users. Check the latest studies of Mektovi.

What is Hot flush?

Hot flush (sudden feelings of heat) is found to be associated with 1,772 drugs and 2,347 conditions by eHealthMe. Check the latest studies of Hot flush.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 03, 2026

6,177 people reported to have side effects when taking Mektovi.
Among them, 17 people (0.28%) have Hot flush.

Among these 17 people:

How long have people been on Mektovi when they have Hot flush? *

What is the age of people who have Hot flush when taking Mektovi? *

What are other drugs people take besides Mektovi? *

What are other side effects people have besides Hot flush? *

Blood Glucose Increased: 12 people, 70.59%
White Blood Cell Count Decreased: 11 people, 64.71%
Abdominal Pain: 11 people, 64.71%
Nipple Disorder (disease of nipple): 11 people, 64.71%
Red Blood Cell Count Decreased: 11 people, 64.71%
High Blood Cholesterol: 11 people, 64.71%
Fatigue (feeling of tiredness): 10 people, 58.82%
Weight Decreased: 10 people, 58.82%
Depressed Mood: 10 people, 58.82%
Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall): 10 people, 58.82%

What are the existing conditions these people have? *

Breast Cancer Female: 9 people, 52.94%
Breast Cancer: 7 people, 41.18%
Malignant Melanoma (skin cancer rises from melancytes): 4 people, 23.53%
Thyroid Cancer Metastatic (thyroid cancer spreads to other part): 1 person, 5.88%
Pulse Abnormal: 1 person, 5.88%
Neuropathy Peripheral (surface nerve damage): 1 person, 5.88%
Neoplasm Malignant (cancer tumour): 1 person, 5.88%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 5.88%
Blood Pressure Abnormal: 1 person, 5.88%

* Approximation only. Some reports may have incomplete information.

Do you take Mektovi and have Hot flush?

- Check whether Hot flush is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Mektovi:

Mektovi (6,179 reports)

Hot flush treatments and more:

Hot flush (91,208 reports)

Browse all side effects of Mektovi:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hot flush:

Hot flush (1,772 drugs)

Browse all the conditions that are associated with Hot flush:

Hot flush (2,347 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on binimetinib (the active ingredients of Mektovi) and Mektovi (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.