Memantine and Liver function test abnormal - a phase IV clinical study of FDA data

Summary:

Liver function test abnormal is reported as a side effect among people who take Memantine (memantine), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Metformin, and have Depression.

The phase IV clinical study analyzes which people have Liver function test abnormal when taking Memantine. It is created by eHealthMe based on reports of 10,128 people who have side effects when taking Memantine from the FDA, and is updated regularly.

What is Memantine?

Memantine has active ingredients of memantine. It is often used in alzheimer's disease. eHealthMe is studying from 10,265 Memantine users. Check the latest studies of Memantine.

What is Liver function test abnormal?

Liver function test abnormal is found to be associated with 1,515 drugs and 1,959 conditions by eHealthMe. Check the latest studies of Liver function test abnormal.

On Apr, 17, 2026

10,128 people reported to have side effects when taking Memantine.
Among them, 42 people (0.41%) have Liver function test abnormal.

Could Memantine cause Liver function test abnormal?

Among these 42 people:

How long have people been on Memantine when they have Liver function test abnormal? *

What is the gender of people who have Liver function test abnormal when taking Memantine? *

female: 39.47 %
male: 60.53 %

What is the age of people who have Liver function test abnormal when taking Memantine? *

What are other drugs people take besides Memantine? *

Metformin: 15 people, 35.71%
Lorazepam: 13 people, 30.95%
Apixaban: 10 people, 23.81%
Sertraline: 10 people, 23.81%
Omeprazole: 10 people, 23.81%
Isosorbide Mononitrate: 9 people, 21.43%
Latanoprost: 9 people, 21.43%
Nitroglycerin: 9 people, 21.43%
Ferrous Fumarate: 9 people, 21.43%
Olanzapine: 9 people, 21.43%

What are other side effects people have besides Liver function test abnormal? *

Jaundice - Yellow Skin (a yellowish pigmentation of the skin): 10 people, 23.81%
Drug-Induced Liver Injury (diseases of the liver that are caused by physician-prescribed medications): 9 people, 21.43%
Hepatotoxicity (chemical-driven liver damage): 4 people, 9.52%
Fatigue (feeling of tiredness): 3 people, 7.14%
Drug Ineffective: 2 people, 4.76%
Haemoglobin Decreased: 1 person, 2.38%
Haematoma (collection of blood outside the blood vessels): 1 person, 2.38%
General Physical Health Deterioration (weak health status): 1 person, 2.38%
Gamma-Glutamyltransferase Increased: 1 person, 2.38%
Food Aversion (we reject certain foods for a reason): 1 person, 2.38%

What are the existing conditions these people have? *

High Blood Pressure: 2 people, 4.76%
Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure): 2 people, 4.76%
Pick's Disease (progressive dementia): 2 people, 4.76%
Pain: 2 people, 4.76%
Cognitive Disorder (mental health disorders affects learning, memory, perception, and problem solving): 2 people, 4.76%
Memory Loss: 2 people, 4.76%
Depression: 2 people, 4.76%
Glaucoma (increased fluid pressure in the eye with vision loss): 1 person, 2.38%
Breast Cancer: 1 person, 2.38%
Bronchopneumopathy: 1 person, 2.38%

* Approximation only. Some reports may have incomplete information.

Do you take Memantine and have Liver function test abnormal?

- Check whether Liver function test abnormal is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Memantine:

Memantine (10,265 reports)

Browse all side effects of Memantine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Liver function test abnormal:

Liver function test abnormal (1,515 drugs)

Browse all the conditions that are associated with Liver function test abnormal:

Liver function test abnormal (1,959 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on memantine (the active ingredients of Memantine) and Memantine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.