Mercaptopurine and Enterocolitis - a phase IV clinical study of FDA data

Summary:

Enterocolitis is reported as a side effect among people who take Mercaptopurine (mercaptopurine), especially for people who are female, 10-19 old, have been taking the drug for < 1 month also take Oncaspar, and have Acute lymphocytic leukemia (all).

The phase IV clinical study analyzes which people have Enterocolitis when taking Mercaptopurine. It is created by eHealthMe based on reports of 22,744 people who have side effects when taking Mercaptopurine from the FDA, and is updated regularly.

What is Mercaptopurine?

Mercaptopurine has active ingredients of mercaptopurine. It is often used in crohn's disease. eHealthMe is studying from 23,013 Mercaptopurine users. Check the latest studies of Mercaptopurine.

What is Enterocolitis?

Enterocolitis (inflammation of the digestive tract, involving enteritis of the small intestine and colitis of the colon) is found to be associated with 660 drugs and 732 conditions by eHealthMe. Check the latest studies of Enterocolitis.

On Aug, 05, 2026

22,744 people reported to have side effects when taking Mercaptopurine.
Among them, 53 people (0.23%) have Enterocolitis.

Could Mercaptopurine cause Enterocolitis?

Among these 53 people:

How long have people been on Mercaptopurine when they have Enterocolitis? *

What is the gender of people who have Enterocolitis when taking Mercaptopurine? *

female: 76.6 %
male: 23.4 %

What is the age of people who have Enterocolitis when taking Mercaptopurine? *

What are other drugs people take besides Mercaptopurine? *

What are other side effects people have besides Enterocolitis? *

Histoplasmosis Disseminated (respiratory infection caused by inhaling the spores of the fungus histoplasma capsulatum): 14 people, 26.42%
Hepatomegaly (abnormal enlargement of the liver): 12 people, 22.64%
Drug-Induced Liver Injury (diseases of the liver that are caused by physician-prescribed medications): 12 people, 22.64%
Constipation: 12 people, 22.64%
Pancreatitis (inflammation of pancreas): 12 people, 22.64%
Anaphylaxis (serious allergic reaction that is rapid in onset and may cause death): 10 people, 18.87%
Granulomatous Liver Disease (a mass of inflamed granulation tissue of liver): 8 people, 15.09%
Pulmonary Granuloma (tiny lump of inflamed tissue in the lungs): 8 people, 15.09%
Sepsis (a severe blood infection that can lead to organ failure and death): 8 people, 15.09%
Cholangitis (infection of the bile duct): 8 people, 15.09%

What are the existing conditions these people have? *

Acute Lymphocytic Leukemia (All) (cancer of the white blood cells characterized by excess lymphoblasts): 17 people, 32.08%
Immunodeficiency Disorders: 8 people, 15.09%
B Precursor Type Acute Leukaemia (lymphoid cancer): 2 people, 3.77%
Adverse Event: 2 people, 3.77%
Threatened Labor: 1 person, 1.89%
Ovulation Induction: 1 person, 1.89%
Itching: 1 person, 1.89%
Foetal Exposure During Pregnancy (exposing your unborn child to contraindicated in pregnancy leads birth defect): 1 person, 1.89%
Escherichia Infection (bacterial infection by escherichia coli): 1 person, 1.89%
B-Cell Type Acute Leukaemia (cancer of the white blood cells): 1 person, 1.89%

* Approximation only. Some reports may have incomplete information.

Do you take Mercaptopurine and have Enterocolitis?

- Check whether Enterocolitis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Mercaptopurine:

Mercaptopurine (23,013 reports)

Enterocolitis treatments and more:

Enterocolitis (7,684 reports)

Browse all side effects of Mercaptopurine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Enterocolitis:

Enterocolitis (660 drugs)

Browse all the conditions that are associated with Enterocolitis:

Enterocolitis (732 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on mercaptopurine (the active ingredients of Mercaptopurine) and Mercaptopurine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.