Mercaptopurine and Radiculopathy - a phase IV clinical study of FDA data

Summary:

Radiculopathy is reported as a side effect among people who take Mercaptopurine (mercaptopurine), especially for people who are female, 10-19 old, also take Cytarabine, and have Acute lymphocytic leukemia (all).

The phase IV clinical study analyzes which people have Radiculopathy when taking Mercaptopurine. It is created by eHealthMe based on reports of 22,744 people who have side effects when taking Mercaptopurine from the FDA, and is updated regularly.

What is Mercaptopurine?

Mercaptopurine has active ingredients of mercaptopurine. It is often used in crohn's disease. eHealthMe is studying from 23,013 Mercaptopurine users. Check the latest studies of Mercaptopurine.

What is Radiculopathy?

Radiculopathy (a set of conditions in which one or more nerves is affected and does not work properly) is found to be associated with 739 drugs and 608 conditions by eHealthMe. Check the latest studies of Radiculopathy.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Sep, 03, 2026

22,744 people reported to have side effects when taking Mercaptopurine.
Among them, 15 people (0.07%) have Radiculopathy.

Could Mercaptopurine cause Radiculopathy?

Among these 15 people:

What is the gender of people who have Radiculopathy when taking Mercaptopurine? *

  • female: 71.43 %
  • male: 28.57 %

What is the age of people who have Radiculopathy when taking Mercaptopurine? *

  • 0-1: 0.0 %
  • 2-9: 28.57 %
  • 10-19: 42.86 %
  • 20-29: 14.29 %
  • 30-39: 0.0 %
  • 40-49: 7.14 %
  • 50-59: 0.0 %
  • 60+: 7.14 %

What are other drugs people take besides Mercaptopurine? *

  1. Methotrexate: 5 people, 33.33%
  2. Cytarabine: 5 people, 33.33%
  3. Hydrocortisone: 4 people, 26.67%
  4. Cyclophosphamide: 3 people, 20.00%
  5. Thioguanine: 2 people, 13.33%
  6. Elspar: 2 people, 13.33%
  7. Remicade: 2 people, 13.33%
  8. Nelarabine: 2 people, 13.33%
  9. Fosamax: 2 people, 13.33%
  10. Benadryl: 2 people, 13.33%

What are other side effects people have besides Radiculopathy? *

  1. Weakness: 8 people, 53.33%
  2. Hypoaesthesia (reduced sense of touch or sensation): 4 people, 26.67%
  3. Subacute Combined Cord Degeneration (subacute combined degeneration of the spinal cord is caused by a vitamin b12 deficiency): 4 people, 26.67%
  4. Pain In Extremity: 3 people, 20.00%
  5. Csf Protein Increased: 3 people, 20.00%
  6. Spinal Osteoarthritis (joint cartilage loss in spine): 3 people, 20.00%
  7. Stress And Anxiety: 3 people, 20.00%
  8. Cataract (clouding of the lens inside the eye): 3 people, 20.00%
  9. Muscle Function Loss: 3 people, 20.00%
  10. Back Pain: 3 people, 20.00%

What are the existing conditions these people have? *

  1. Acute Lymphocytic Leukemia (All) (cancer of the white blood cells characterized by excess lymphoblasts): 7 people, 46.67%
  2. Pain: 2 people, 13.33%
  3. Osteopenia (a condition where bone mineral density is lower than normal): 2 people, 13.33%
  4. Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 2 people, 13.33%
  5. High Blood Cholesterol: 2 people, 13.33%
  6. Breast Cancer: 2 people, 13.33%
  7. Transient Ischaemic Attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow)): 1 person, 6.67%
  8. Dyspnea (difficult or laboured breathing): 1 person, 6.67%
  9. Arthropod Sting (arthropod bite): 1 person, 6.67%
  10. Autoimmune Hepatitis: 1 person, 6.67%

* Approximation only. Some reports may have incomplete information.

Do you take Mercaptopurine and have Radiculopathy?

- Check whether Radiculopathy is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Mercaptopurine:

Radiculopathy treatments and more:

How severe was Radiculopathy and when was it recovered:

Expand to all the drugs that have ingredients of mercaptopurine:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Mercaptopurine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Radiculopathy:

Browse all the conditions that are associated with Radiculopathy:

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on mercaptopurine (the active ingredients of Mercaptopurine) and Mercaptopurine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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