Mesna and Osteoporosis - a phase IV clinical study of FDA data

Summary:

Osteoporosis is reported as a side effect among people who take Mesna (mesna), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Aredia, and have Multiple myeloma.

The phase IV clinical study analyzes which people have Osteoporosis when taking Mesna. It is created by eHealthMe based on reports of 9,641 people who have side effects when taking Mesna from the FDA, and is updated regularly.

What is Mesna?

Mesna has active ingredients of mesna. eHealthMe is studying from 9,647 Mesna users. Check the latest studies of Mesna.

What is Osteoporosis?

Osteoporosis (bones weak and more likely to break) is found to be associated with 1,806 drugs and 1,904 conditions by eHealthMe. Check the latest studies of Osteoporosis.

On Aug, 05, 2026

9,641 people reported to have side effects when taking Mesna.
Among them, 25 people (0.26%) have Osteoporosis.

Among these 25 people:

How long have people been on Mesna when they have Osteoporosis? *

What is the gender of people who have Osteoporosis when taking Mesna? *

female: 34.78 %
male: 65.22 %

What is the age of people who have Osteoporosis when taking Mesna? *

What are other drugs people take besides Mesna? *

What are other side effects people have besides Osteoporosis? *

Pain: 18 people, 72.00%
Impaired Healing: 18 people, 72.00%
Haematuria (presence of blood in urine): 18 people, 72.00%
Bone Disorder: 18 people, 72.00%
Sinusitis (inflammation of sinus): 18 people, 72.00%
Stress And Anxiety: 18 people, 72.00%
Multiple Myeloma (cancer of the plasma cells): 17 people, 68.00%
Osteonecrosis Of Jaw (death of bone of jaw): 16 people, 64.00%
Fungal Nail Infection: 16 people, 64.00%
Hyperkeratosis (thickening of the outer layer of the skin): 16 people, 64.00%

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 13 people, 52.00%
Urination - Excessive Volume: 2 people, 8.00%
Sleep Paralysis (waking up and unable to move or speak): 2 people, 8.00%
Anaesthesia: 2 people, 8.00%
Asthma: 2 people, 8.00%
Cardiotoxicity (damage to the heart muscle): 2 people, 8.00%
Central Nervous System Stimulation: 2 people, 8.00%
Constipation: 2 people, 8.00%
Gastritis (inflammation of stomach): 2 people, 8.00%
Herpes Zoster: 2 people, 8.00%

* Approximation only. Some reports may have incomplete information.

Do you take Mesna and have Osteoporosis?

- Check whether Osteoporosis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Mesna:

Mesna (9,647 reports)

Osteoporosis treatments and more:

Osteoporosis (290,734 reports)

Browse all side effects of Mesna:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Osteoporosis:

Osteoporosis (1,806 drugs)

Browse all the conditions that are associated with Osteoporosis:

Osteoporosis (1,904 conditions)

Related publications that referenced our studies

Hirschmann S, Gibel A, Tsvelikhovsky I, Lisker A, "Late-Onset Psychosis and Risedronate Treatment for Osteoporosis: A Case Report", Clinical schizophrenia & related psychoses, 2013 May .
Ko KD, Cho BL, "Risedronate-related Localized Amnesia in an Elderly Patient with Osteoporosis", Journal of the Korean Geriatrics Society, 2012 Dec .
Lee WY, Sun LM, Lin MC, Liang JA, Chang SN, Sung FC, Muo CH, Kao CH, "A higher dosage of oral alendronate will increase the subsequent cancer risk of osteoporosis patients in Taiwan: a population-based cohort study", PloS one, 2012 Dec .
Hirschmann S, Gibel A, Tsvelikhovsky I, Lisker A, "Late-Onset Psychosis and Risedronate Treatment for Osteoporosis: A Case Report", Clinical schizophrenia & related psychoses, 2013 May .
Ko KD, Cho BL, "Risedronate-related Localized Amnesia in an Elderly Patient with Osteoporosis", Journal of the Korean Geriatrics Society, 2012 Dec .
Lee WY, Sun LM, Lin MC, Liang JA, Chang SN, Sung FC, Muo CH, Kao CH, "A higher dosage of oral alendronate will increase the subsequent cancer risk of osteoporosis patients in Taiwan: a population-based cohort study", PloS one, 2012 Dec .

How the study uses the data?

The study uses data from the FDA. It is based on mesna (the active ingredients of Mesna) and Mesna (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.