Metaxalone and Ulcerative colitis - a phase IV clinical study of FDA data

Summary:

Ulcerative colitis is reported as a side effect among people who take Metaxalone (metaxalone), especially for people who are female, 60+ old, also take Cymbalta, and have Drowsiness.

The phase IV clinical study analyzes which people have Ulcerative colitis when taking Metaxalone. It is created by eHealthMe based on reports of 4,277 people who have side effects when taking Metaxalone from the FDA, and is updated regularly.

What is Metaxalone?

Metaxalone has active ingredients of metaxalone. It is often used in back pain. eHealthMe is studying from 4,452 Metaxalone users. Check the latest studies of Metaxalone.

What is Ulcerative colitis?

Ulcerative colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine) is found to be associated with 1,199 drugs and 2,052 conditions by eHealthMe. Check the latest studies of Ulcerative colitis.

On Jul, 21, 2026

4,277 people reported to have side effects when taking Metaxalone.
Among them, 12 people (0.28%) have Ulcerative colitis.

Could Metaxalone cause Ulcerative colitis?

Among these 12 people:

What is the gender of people who have Ulcerative colitis when taking Metaxalone? *

female: 87.5 %
male: 12.5 %

What is the age of people who have Ulcerative colitis when taking Metaxalone? *

What are other drugs people take besides Metaxalone? *

What are other side effects people have besides Ulcerative colitis? *

Weight Increased: 4 people, 33.33%
Sedation: 4 people, 33.33%
Irritable Bowel Syndrome: 4 people, 33.33%
Haemorrhoids (a swollen vein or group of veins in the region of the anus): 4 people, 33.33%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 33.33%
Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall): 4 people, 33.33%
Rickets (softening of bones): 4 people, 33.33%
Diverticulum (out pouching of a hollow (or a fluid-filled) structure in the body): 4 people, 33.33%
Hernia (hernia happens when part of an internal organ or tissue bulges through a weak area of muscle): 4 people, 33.33%
Anaemia Vitamin B12 Deficiency: 4 people, 33.33%

What are the existing conditions these people have? *

Sleep Apnea Syndrome: 4 people, 33.33%
High Blood Pressure: 4 people, 33.33%
Fibromyalgia (a long-term condition which causes pain all over the body): 4 people, 33.33%
Drowsiness: 4 people, 33.33%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 2 people, 16.67%
Pain: 1 person, 8.33%
Osteoarthritis (a joint disease caused by cartilage loss in a joint): 1 person, 8.33%
Insomnia (sleeplessness): 1 person, 8.33%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Metaxalone and have Ulcerative colitis?

- Check whether Ulcerative colitis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Metaxalone:

Metaxalone (4,452 reports)

Browse all side effects of Metaxalone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Ulcerative colitis:

Ulcerative colitis (1,199 drugs)

Browse all the conditions that are associated with Ulcerative colitis:

Ulcerative colitis (2,052 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on metaxalone (the active ingredients of Metaxalone) and Metaxalone (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.