Metformin and Skin blushing/flushing - a phase IV clinical study of FDA data

Summary:

Skin blushing/flushing is found among people who take Metformin, especially for people who are female, 60+ old, have been taking the drug for 1 - 2 years.

The phase IV clinical study analyzes which people take Metformin and have Skin blushing/flushing. It is created by eHealthMe based on reports of 395,495 people who have side effects when taking Metformin from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Aug, 11, 2023

395,495 people reported to have side effects when taking Metformin.
Among them, 3,096 people (0.78%) have Skin blushing/flushing.

What is Metformin?

Metformin has active ingredients of metformin hydrochloride. It is often used in diabetes. eHealthMe is studying from 440,868 Metformin users for its effectiveness, alternative drugs and more.

What is Skin blushing/flushing?

Skin blushing/flushing (a sudden reddening of the face, neck) is found to be associated with 3,567 drugs and 2,858 conditions by eHealthMe.

Number of Metformin and Skin blushing/flushing reports submitted per year:

Could Metformin cause Skin blushing/flushing?

* Approximation only. Some reports may have incomplete information.

Do you take Metformin and have Skin blushing/flushing?

Check whether Skin blushing/flushing is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related publications that referenced our studies

T.Audi Yanto, I.Huang, F.Nathania Kosasih, NP Hardjo Lugito, "Nightmare and Abnormal Dreams: Rare Side Effects of Metformin?", Case Reports in Endocrinology, 2018 Jan .
Al-Hamdy RA, "Assessment of electrolytes and HbA1c in type 2 diabetic patients using metformin and evaluation of guidelines obedience regarding renal impairment", J.Thi-Qar Sci., 2015 Jan .
Wiwanitkit S, Wiwanitkit V, "Metformin and sleep disorders", Indian journal of endocrinology and metabolism, 2012 Jan .

Related studies

How severe was Skin blushing/flushing and when was it recovered:

Skin blushing/flushing in Metformin

Expand to all the drugs that have ingredients of metformin hydrochloride:

Skin blushing/flushing and drugs with ingredients of metformin hydrochloride (3,503 reports)

Alternative drugs to, pros and cons of Metformin:

Metformin (440,868 reports)

Common Metformin side effects:

Diarrhea: 28,112 reports
Fatigue (feeling of tiredness): 22,049 reports
Drug ineffective: 20,041 reports
Weight decreased: 19,088 reports
Nausea and vomiting: 17,857 reports
Lactic acidosis (low ph in body tissues): 17,478 reports
Breathing difficulty: 16,617 reports

Browse all side effects of Metformin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Skin blushing/flushing treatments and more:

Skin blushing/flushing (113,685 reports)

COVID vaccines that are related to Skin blushing/flushing:

Common drugs associated with Skin blushing/flushing:

All the drugs that are associated with Skin blushing/flushing:

Skin blushing/flushing (3,567 drugs)

Common conditions associated with Skin blushing/flushing:

Multiple sclerosis: 20,241 reports
High blood cholesterol: 11,089 reports
Primary pulmonary hypertension: 5,307 reports
High blood pressure: 3,177 reports

All the conditions that are associated with Skin blushing/flushing:

Skin blushing/flushing (2,858 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on metformin hydrochloride (the active ingredients of Metformin) and Metformin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.