Metformin and Urinary casts - a phase IV clinical study of FDA data

Summary:

Urinary casts is reported as a side effect among people who take Metformin (metformin hydrochloride), especially for people who are male, 60+ old, have been taking the drug for 1 - 6 months also take Fosamax, and have High blood pressure.

The phase IV clinical study analyzes which people have Urinary casts when taking Metformin. It is created by eHealthMe based on reports of 453,860 people who have side effects when taking Metformin from the FDA, and is updated regularly.

What is Metformin?

Metformin has active ingredients of metformin hydrochloride. It is often used in diabetes. eHealthMe is studying from 465,354 Metformin users. Check the latest studies of Metformin.

What is Urinary casts?

Urinary casts is found to be associated with 113 drugs and 371 conditions by eHealthMe. Check the latest studies of Urinary casts.

On May, 23, 2026

453,860 people reported to have side effects when taking Metformin.
Among them, 24 people (0.01%) have Urinary casts.

Among these 24 people:

How long have people been on Metformin when they have Urinary casts? *

What is the gender of people who have Urinary casts when taking Metformin? *

female: 47.83 %
male: 52.17 %

What is the age of people who have Urinary casts when taking Metformin? *

What are other drugs people take besides Metformin? *

What are other side effects people have besides Urinary casts? *

Blood Creatinine Increased: 9 people, 37.50%
Protein Urine Present: 7 people, 29.17%
White Blood Cells Urine Positive: 6 people, 25.00%
Renal Tubular Necrosis (death of kidney tubules): 6 people, 25.00%
Bacterial Test Positive: 6 people, 25.00%
Urine Abnormality: 6 people, 25.00%
Urine Protein/creatinine Ratio Increased: 6 people, 25.00%
Acute Kidney Failure: 6 people, 25.00%
Blood Urea Increased: 5 people, 20.83%
Urinary Sediment Present: 5 people, 20.83%

What are the existing conditions these people have? *

High Blood Pressure: 6 people, 25.00%
Cardiac Failure Congestive: 4 people, 16.67%
Hereditary Neuropathic Amyloidosis (hereditary- diseases resulting from abnormal deposition of certain proteins (amyloid) in various bodily areas by problems with signals from the nerves): 4 people, 16.67%
Hyperlipidaemia (presence of excess lipids in the blood): 3 people, 12.50%
Osteoporosis (bones weak and more likely to break): 3 people, 12.50%
Wound Infection Staphylococcal: 1 person, 4.17%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 1 person, 4.17%
Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 1 person, 4.17%
Dry Mouth: 1 person, 4.17%
High Blood Cholesterol: 1 person, 4.17%

* Approximation only. Some reports may have incomplete information.

Do you take Metformin and have Urinary casts?

- Check whether Urinary casts is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Metformin:

Metformin (465,354 reports)

Urinary casts treatments and more:

Urinary casts (855 reports)

Browse all side effects of Metformin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Urinary casts:

Urinary casts (113 drugs)

Browse all the conditions that are associated with Urinary casts:

Urinary casts (371 conditions)

Related publications that referenced our studies

T.Audi Yanto, I.Huang, F.Nathania Kosasih, NP Hardjo Lugito, "Nightmare and Abnormal Dreams: Rare Side Effects of Metformin?", Case Reports in Endocrinology, 2018 Jan .
Al-Hamdy RA, "Assessment of electrolytes and HbA1c in type 2 diabetic patients using metformin and evaluation of guidelines obedience regarding renal impairment", J.Thi-Qar Sci., 2015 Jan .
Wiwanitkit S, Wiwanitkit V, "Metformin and sleep disorders", Indian journal of endocrinology and metabolism, 2012 Jan .
T.Audi Yanto, I.Huang, F.Nathania Kosasih, NP Hardjo Lugito, "Nightmare and Abnormal Dreams: Rare Side Effects of Metformin?", Case Reports in Endocrinology, 2018 Jan .
Al-Hamdy RA, "Assessment of electrolytes and HbA1c in type 2 diabetic patients using metformin and evaluation of guidelines obedience regarding renal impairment", J.Thi-Qar Sci., 2015 Jan .
Wiwanitkit S, Wiwanitkit V, "Metformin and sleep disorders", Indian journal of endocrinology and metabolism, 2012 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on metformin hydrochloride (the active ingredients of Metformin) and Metformin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.