Methimazole and Photophobia - a phase IV clinical study of FDA data

Summary:

Photophobia is reported as a side effect among people who take Methimazole (methimazole), especially for people who are female, 60+ old, have been taking the drug for 1 - 6 months also take Tepezza, and have Endocrine ophthalmopathy.

The phase IV clinical study analyzes which people have Photophobia when taking Methimazole. It is created by eHealthMe based on reports of 7,420 people who have side effects when taking Methimazole from the FDA, and is updated regularly.

What is Methimazole?

Methimazole has active ingredients of methimazole. It is often used in hyperthyroidism. eHealthMe is studying from 8,016 Methimazole users. Check the latest studies of Methimazole.

What is Photophobia?

Photophobia (extreme sensitivity to light) is found to be associated with 1,295 drugs and 1,831 conditions by eHealthMe. Check the latest studies of Photophobia.



On Apr, 24, 2026

7,420 people reported to have side effects when taking Methimazole.
Among them, 13 people (0.18%) have Photophobia.

Could Methimazole cause Photophobia?

Among these 13 people:

How long have people been on Methimazole when they have Photophobia? *

  • < 1 month: 0.0 %
  • 1 - 6 months: 100 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Photophobia when taking Methimazole? *

  • female: 83.33 %
  • male: 16.67 %

What is the age of people who have Photophobia when taking Methimazole? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 20 %
  • 30-39: 20 %
  • 40-49: 0.0 %
  • 50-59: 0.0 %
  • 60+: 60 %

What are other drugs people take besides Methimazole? *

  1. Tepezza: 7 people, 53.85%
  2. Amlodipine: 4 people, 30.77%
  3. Gabapentin: 3 people, 23.08%
  4. Hydrochlorothiazide: 3 people, 23.08%
  5. Selenium: 2 people, 15.38%
  6. Novolog: 2 people, 15.38%
  7. Omeprazole: 2 people, 15.38%
  8. Lisinopril: 2 people, 15.38%
  9. Restasis: 2 people, 15.38%
  10. Basaglar: 2 people, 15.38%

What are other side effects people have besides Photophobia? *

  1. Headache (pain in head): 7 people, 53.85%
  2. Ocular Hyperaemia (an abnormally large amount of blood in eye): 5 people, 38.46%
  3. Eye Pruritus (eye itching): 3 people, 23.08%
  4. Nausea (feeling of having an urge to vomit): 3 people, 23.08%
  5. Tinnitus (a ringing in the ears): 3 people, 23.08%
  6. Eye Irritation: 3 people, 23.08%
  7. Diplopia (double vision): 3 people, 23.08%
  8. Dry Eyes (lack of adequate tears): 3 people, 23.08%
  9. Ear Discomfort: 3 people, 23.08%
  10. Dry Skin: 2 people, 15.38%

What are the existing conditions these people have? *

  1. Endocrine Ophthalmopathy (increased water content of retroocular orbital tissues; associated with thyroid disease, usually hyperthyroidism): 5 people, 38.46%
  2. Wheezing (a high-pitched whistling sound made while you breath): 1 person, 7.69%
  3. Stress And Anxiety: 1 person, 7.69%
  4. Neurotrophic Keratopathy (decreased corneal sensitivity and poor corneal healing): 1 person, 7.69%
  5. Depression: 1 person, 7.69%
  6. Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 1 person, 7.69%
  7. Cerebral Venous Thrombosis (clot in brains venous blood system): 1 person, 7.69%
  8. Blood Pressure Abnormal: 1 person, 7.69%
  9. Basedow's Disease (autoimmune disease where the thyroid is overactive, producing an excessive amount of thyroid hormones): 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

Do you take Methimazole and have Photophobia?

- Check whether Photophobia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Methimazole:

Photophobia treatments and more:

How severe was Photophobia and when was it recovered:

Expand to all the drugs that have ingredients of methimazole:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Methimazole:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Photophobia:

Browse all the conditions that are associated with Photophobia:


How the study uses the data?

The study uses data from the FDA. It is based on methimazole (the active ingredients of Methimazole) and Methimazole (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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