Methimazole and Transaminases increased - a phase IV clinical study of FDA data

Summary:

Transaminases increased is reported as a side effect among people who take Methimazole (methimazole), especially for people who are male, 50-59 old, have been taking the drug for < 1 month also take Hydrocortisone, and have Arrhythmias.

The phase IV clinical study analyzes which people have Transaminases increased when taking Methimazole. It is created by eHealthMe based on reports of 7,420 people who have side effects when taking Methimazole from the FDA, and is updated regularly.

What is Methimazole?

Methimazole has active ingredients of methimazole. It is often used in hyperthyroidism. eHealthMe is studying from 8,016 Methimazole users. Check the latest studies of Methimazole.

What is Transaminases increased?

Transaminases increased is found to be associated with 1,155 drugs and 1,514 conditions by eHealthMe. Check the latest studies of Transaminases increased.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 03, 2026

7,420 people reported to have side effects when taking Methimazole.
Among them, 16 people (0.22%) have Transaminases increased.

Could Methimazole cause Transaminases increased?

Among these 16 people:

How long have people been on Methimazole when they have Transaminases increased? *

What is the gender of people who have Transaminases increased when taking Methimazole? *

female: 50 %
male: 50 %

What is the age of people who have Transaminases increased when taking Methimazole? *

What are other drugs people take besides Methimazole? *

What are other side effects people have besides Transaminases increased? *

Drug Ineffective: 4 people, 25.00%
Hyperbilirubinaemia (excess of bilirubin in the blood): 3 people, 18.75%
Leukopenia (less number of white blood cells in blood): 3 people, 18.75%
Live Birth: 2 people, 12.50%
Cardiac Arrest: 2 people, 12.50%
Alanine Aminotransferase Increased: 2 people, 12.50%
Aspartate Aminotransferase Increased: 2 people, 12.50%
Nausea And Vomiting: 2 people, 12.50%
Nausea (feeling of having an urge to vomit): 2 people, 12.50%
Maternal Exposure During Pregnancy (use of substance during pregnancy): 2 people, 12.50%

What are the existing conditions these people have? *

Thyrotoxic Crisis (a life threatening condition due to excess secretion of thyroid hormone): 1 person, 6.25%
Metastatic Malignant Melanoma (spreadable cancer tumour of melanine): 1 person, 6.25%
Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 1 person, 6.25%
Bacterial Infection: 1 person, 6.25%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 1 person, 6.25%
Arrhythmias (irregular heartbeat): 1 person, 6.25%

* Approximation only. Some reports may have incomplete information.

Do you take Methimazole and have Transaminases increased?

- Check whether Transaminases increased is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Methimazole:

Methimazole (8,016 reports)

Browse all side effects of Methimazole:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Transaminases increased:

Transaminases increased (1,155 drugs)

Browse all the conditions that are associated with Transaminases increased:

Transaminases increased (1,514 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on methimazole (the active ingredients of Methimazole) and Methimazole (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.