Methotrexate and Paronychia - a phase IV clinical study of FDA data

Summary:

We study 517,446 people who have side effects when taking Methotrexate. Paronychia is found, especially among people who are female, 60+ old, have been taking the drug for < 1 month, also take Humira and have Psoriatic arthropathy.

The phase IV clinical study analyzes which people take Methotrexate and have Paronychia. It is created by eHealthMe based on reports from the FDA, and is updated regularly. You may use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 700+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Jul, 04, 2023

517,446 people reported to have side effects when taking Methotrexate.
Among them, 182 people (0.04%) have Paronychia.

What is Methotrexate?

Methotrexate has active ingredients of methotrexate sodium. It is used in rheumatoid arthritis. Currently, eHealthMe is studying from 571,355 Methotrexate users.

What is Paronychia?

Paronychia (infection in the tissues adjacent to a nail on a finger or toe) is found to be associated with 1,274 drugs and 693 conditions by eHealthMe. Currently, we are studying 5,570 people who have Paronychia.

Number of Methotrexate and Paronychia reports submitted per year:

* Approximation only. Some reports may have incomplete information.

Do you take Methotrexate and have Paronychia?

Check whether Paronychia is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related publications that referenced our studies

Henien M, Carey B, Hullah E, Sproat C, Patel V, "methotrexate-associated osteonecrosis of the jaw: A report of two cases", Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology, 2017 Dec .

Related studies

Methotrexate side effects by duration, gender and age:

Methotrexate side effects (571,355 reports)

Paronychia treatments and more:

Paronychia (5,570 reports)

Common drugs associated with Paronychia:

All the drugs that are associated with Paronychia:

Paronychia (1,274 drugs)

Common conditions associated with Paronychia:

Colon cancer: 459 reports
Lung cancer - non-small cell: 401 reports
Rheumatoid arthritis: 246 reports
High blood pressure: 226 reports
Breast cancer: 215 reports
Preventive health care: 208 reports

All the conditions that are associated with Paronychia:

Paronychia (693 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on methotrexate sodium (the active ingredients of Methotrexate) and Methotrexate (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 700+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.