Methyldopa and Hypokalemia - a phase IV clinical study of FDA data

Summary:

Hypokalemia is reported as a side effect among people who take Methyldopa (methyldopa), especially for people who are female, 50-59 old, also take Nasonex, and have Pain.

The phase IV clinical study analyzes which people have Hypokalemia when taking Methyldopa. It is created by eHealthMe based on reports of 6,345 people who have side effects when taking Methyldopa from the FDA, and is updated regularly.

What is Methyldopa?

Methyldopa has active ingredients of methyldopa. It is often used in high blood pressure. eHealthMe is studying from 6,475 Methyldopa users. Check the latest studies of Methyldopa.

What is Hypokalemia?

Hypokalemia (low potassium) is found to be associated with 2,086 drugs and 3,091 conditions by eHealthMe. Check the latest studies of Hypokalemia.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 04, 2026

6,345 people reported to have side effects when taking Methyldopa.
Among them, 52 people (0.82%) have Hypokalemia.

Among these 52 people:

What is the gender of people who have Hypokalemia when taking Methyldopa? *

female: 63.83 %
male: 36.17 %

What is the age of people who have Hypokalemia when taking Methyldopa? *

What are other drugs people take besides Methyldopa? *

What are other side effects people have besides Hypokalemia? *

Nausea And Vomiting: 31 people, 59.62%
Weakness: 26 people, 50.00%
Nausea (feeling of having an urge to vomit): 25 people, 48.08%
Diarrhea: 24 people, 46.15%
Headache (pain in head): 22 people, 42.31%
Joint Pain: 21 people, 40.38%
Sinusitis (inflammation of sinus): 21 people, 40.38%
Dyspnea (difficult or laboured breathing): 21 people, 40.38%
Weight Decreased: 20 people, 38.46%
Fatigue (feeling of tiredness): 20 people, 38.46%

What are the existing conditions these people have? *

Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 17 people, 32.69%
Pain: 17 people, 32.69%
Nausea (feeling of having an urge to vomit): 6 people, 11.54%
Lip And/or Oral Cavity Cancer (cancer of lip or mouth): 6 people, 11.54%
Suicide Attempt: 5 people, 9.62%
Indigestion: 4 people, 7.69%
Gestational Diabetes (diabetes in pregnancy): 4 people, 7.69%
Discomfort: 3 people, 5.77%
Cough: 3 people, 5.77%
Diabetes: 3 people, 5.77%

* Approximation only. Some reports may have incomplete information.

Do you take Methyldopa and have Hypokalemia?

- Check whether Hypokalemia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Methyldopa:

Methyldopa (6,475 reports)

Hypokalemia treatments and more:

Hypokalemia (72,278 reports)

Browse all side effects of Methyldopa:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hypokalemia:

Hypokalemia (2,086 drugs)

Browse all the conditions that are associated with Hypokalemia:

Hypokalemia (3,091 conditions)

Related publications that referenced our studies

Izgi C, Erdem G, Mansuroglu D, Kurtoglu N, Kara M, Gunesdogdu F, "Severe hypokalemia probably associated with sertraline use", Annals of Pharmacotherapy, 2014 Jan .
Izgi C, Erdem G, Mansuroglu D, Kurtoglu N, Kara M, Gunesdogdu F, "Severe hypokalemia probably associated with sertraline use", Annals of Pharmacotherapy, 2014 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on methyldopa (the active ingredients of Methyldopa) and Methyldopa (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.