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Methylphenidate hydrochloride and Anaphylaxis - a phase IV clinical study of FDA data

Summary:

Anaphylaxis is reported as a side effect among people who take Methylphenidate hydrochloride (methylphenidate hydrochloride), especially for people who are male, 10-19 old, also take Singulair, and have Asthma.

The phase IV clinical study analyzes which people have Anaphylaxis when taking Methylphenidate hydrochloride. It is created by eHealthMe based on reports of 6,364 people who have side effects when taking Methylphenidate hydrochloride from the FDA, and is updated regularly.

What is Methylphenidate hydrochloride?

Methylphenidate hydrochloride has active ingredients of methylphenidate hydrochloride. It is often used in attention deficit hyperactivity disorder. eHealthMe is studying from 6,823 Methylphenidate hydrochloride users. Check the latest studies of Methylphenidate hydrochloride.

What is Anaphylaxis?

Anaphylaxis (serious allergic reaction that is rapid in onset and may cause death) is found to be associated with 1,927 drugs and 2,860 conditions by eHealthMe. Check the latest studies of Anaphylaxis.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 31, 2026

6,364 people reported to have side effects when taking Methylphenidate hydrochloride.
Among them, 16 people (0.25%) have Anaphylaxis.

Could Methylphenidate hydrochloride cause Anaphylaxis?

Among these 16 people:

What is the gender of people who have Anaphylaxis when taking Methylphenidate hydrochloride? *

  • female: 33.33 %
  • male: 66.67 %

What is the age of people who have Anaphylaxis when taking Methylphenidate hydrochloride? *

  • 0-1: 0.0 %
  • 2-9: 7.69 %
  • 10-19: 69.23 %
  • 20-29: 15.38 %
  • 30-39: 0.0 %
  • 40-49: 7.69 %
  • 50-59: 0.0 %
  • 60+: 0.0 %

What are other drugs people take besides Methylphenidate hydrochloride? *

  1. Xolair: 7 people, 43.75%
  2. Ventolin: 7 people, 43.75%
  3. Symbicort: 7 people, 43.75%
  4. Singulair: 7 people, 43.75%
  5. Xywav: 1 person, 6.25%
  6. Concerta: 1 person, 6.25%
  7. Imuran: 1 person, 6.25%
  8. Fish Oil: 1 person, 6.25%
  9. Escitalopram: 1 person, 6.25%
  10. Epipen: 1 person, 6.25%

What are other side effects people have besides Anaphylaxis? *

  1. Dyspnea (difficult or laboured breathing): 8 people, 50.00%
  2. Rashes (redness): 8 people, 50.00%
  3. Cough: 7 people, 43.75%
  4. Sputum Discolored: 7 people, 43.75%
  5. Middle Insomnia (difficulty returning to sleep after awakening either in the middle of the night): 7 people, 43.75%
  6. Asthma: 7 people, 43.75%
  7. Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters): 7 people, 43.75%
  8. The Flu (the flu is caused by an influenza virus): 7 people, 43.75%
  9. Rhinitis (a medical term for irritation and inflammation of the mucous membrane inside the nose): 7 people, 43.75%
  10. Insomnia (sleeplessness): 6 people, 37.50%

What are the existing conditions these people have? *

  1. Hypersensitivity: 7 people, 43.75%
  2. Asthma: 7 people, 43.75%
  3. Respiratory Tract Infection: 2 people, 12.50%
  4. Otitis (ear infection): 2 people, 12.50%
  5. Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 1 person, 6.25%
  6. Otitis Media Acute (rapid inflammation of the middle ear): 1 person, 6.25%
  7. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 1 person, 6.25%
  8. Inflammatory Bowel Disease: 1 person, 6.25%
  9. Drowsiness: 1 person, 6.25%
  10. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 1 person, 6.25%

* Approximation only. Some reports may have incomplete information.

Do you take Methylphenidate hydrochloride and have Anaphylaxis?

- Check whether Anaphylaxis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Methylphenidate hydrochloride:

Anaphylaxis treatments and more:

How severe was Anaphylaxis and when was it recovered:

Expand to all the drugs that have ingredients of methylphenidate hydrochloride:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Methylphenidate hydrochloride:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Anaphylaxis:

Browse all the conditions that are associated with Anaphylaxis:

Related publications that referenced our studies

How the study uses the data?

The study uses data from the FDA. It is based on methylphenidate hydrochloride (the active ingredients of Methylphenidate hydrochloride) and Methylphenidate hydrochloride (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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