Metopirone and Acute kidney failure - a phase IV clinical study of FDA data

Summary:

Acute kidney failure is reported as a side effect among people who take Metopirone (metyrapone), especially for people who are female, 40-49 old, have been taking the drug for 6 - 12 months also take Exjade, and have Cushing's syndrome.

The phase IV clinical study analyzes which people have Acute kidney failure when taking Metopirone. It is created by eHealthMe based on reports of 532 people who have side effects when taking Metopirone from the FDA, and is updated regularly.

What is Metopirone?

Metopirone has active ingredients of metyrapone. It is often used in low iron. eHealthMe is studying from 550 Metopirone users. Check the latest studies of Metopirone.

What is Acute kidney failure?

Acute kidney failure is found to be associated with 2,835 drugs and 4,500 conditions by eHealthMe. Check the latest studies of Acute kidney failure.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 30, 2026

532 people reported to have side effects when taking Metopirone.
Among them, 11 people (2.07%) have Acute kidney failure.

Could Metopirone cause Acute kidney failure?

Among these 11 people:

How long have people been on Metopirone when they have Acute kidney failure? *

What is the gender of people who have Acute kidney failure when taking Metopirone? *

female: 63.64 %
male: 36.36 %

What is the age of people who have Acute kidney failure when taking Metopirone? *

What are other drugs people take besides Metopirone? *

What are other side effects people have besides Acute kidney failure? *

Deep Venous Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 5 people, 45.45%
Cellulitis (infection under the skin): 4 people, 36.36%
Pulmonary Embolism (blockage of the main artery of the lung): 4 people, 36.36%
Hypotension (abnormally low blood pressure): 4 people, 36.36%
Breathing - Slowed Or Stopped: 4 people, 36.36%
Abdominal Pain: 3 people, 27.27%
Blood Amylase Increased: 3 people, 27.27%
Pancreatitis (inflammation of pancreas): 3 people, 27.27%
Nausea And Vomiting: 3 people, 27.27%
Lipase Increased: 3 people, 27.27%

What are the existing conditions these people have? *

Cushing's Syndrome (obesity, a rounded face, increased fat): 6 people, 54.55%
Haemochromatosis (body to absorb more iron than usual from food): 3 people, 27.27%
Pulmonary Embolism (blockage of the main artery of the lung): 1 person, 9.09%
Medullary Thyroid Cancer (type of thyroid cancer that develops in the parafollicular cells of the thyroid gland): 1 person, 9.09%
Deep Venous Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Metopirone and have Acute kidney failure?

- Check whether Acute kidney failure is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Metopirone:

Metopirone (550 reports)

Browse all side effects of Metopirone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Acute kidney failure:

Acute kidney failure (2,835 drugs)

Browse all the conditions that are associated with Acute kidney failure:

Acute kidney failure (4,500 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on metyrapone (the active ingredients of Metopirone) and Metopirone (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.