Mexitil and Urinary retention - a phase IV clinical study of FDA data

Summary:

Urinary retention is reported as a side effect among people who take Mexitil (mexiletine hydrochloride), especially for people who are male, 60+ old, have been taking the drug for 6 - 12 months also take Lasix, and have Lupus nephritis.

The phase IV clinical study analyzes which people have Urinary retention when taking Mexitil. It is created by eHealthMe based on reports of 1,881 people who have side effects when taking Mexitil from the FDA, and is updated regularly.

What is Mexitil?

Mexitil has active ingredients of mexiletine hydrochloride. eHealthMe is studying from 1,893 Mexitil users. Check the latest studies of Mexitil.

What is Urinary retention?

Urinary retention (the inability to completely or partially empty the bladder) is found to be associated with 1,570 drugs and 1,740 conditions by eHealthMe. Check the latest studies of Urinary retention.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 21, 2026

1,881 people reported to have side effects when taking Mexitil.
Among them, 16 people (0.85%) have Urinary retention.

Among these 16 people:

How long have people been on Mexitil when they have Urinary retention? *

What is the gender of people who have Urinary retention when taking Mexitil? *

female: 6.25 %
male: 93.75 %

What is the age of people who have Urinary retention when taking Mexitil? *

What are other drugs people take besides Mexitil? *

What are other side effects people have besides Urinary retention? *

Prostate Cancer: 11 people, 68.75%
Tremor (trembling or shaking movements in one or more parts of your body): 8 people, 50.00%
Nephrotic Syndrome (kidney disease with proteinuria, hypoalbuminemia, and oedema): 8 people, 50.00%
Pleural Effusion (water on the lungs): 7 people, 43.75%
Haematuria (presence of blood in urine): 5 people, 31.25%
Enlarged Prostate: 5 people, 31.25%
Urinary Tract Infection: 4 people, 25.00%
Bladder Spasm: 3 people, 18.75%
Intestinal Obstruction: 2 people, 12.50%
Diabetes: 2 people, 12.50%

What are the existing conditions these people have? *

Lupus Nephritis (a chronic inflammatory autoimmune disorder that may affect kidney tissue): 8 people, 50.00%
High Blood Pressure: 6 people, 37.50%
Stable Angina (a constant chest pain): 3 people, 18.75%
Constipation: 3 people, 18.75%
Diabetes: 3 people, 18.75%
Osteoarthritis (a joint disease caused by cartilage loss in a joint): 3 people, 18.75%
Oedema (fluid collection in tissue): 3 people, 18.75%
Neuropathy Peripheral (surface nerve damage): 3 people, 18.75%
Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 3 people, 18.75%
Dyslipidaemia (abnormal amount of lipids): 3 people, 18.75%

* Approximation only. Some reports may have incomplete information.

Do you take Mexitil and have Urinary retention?

- Check whether Urinary retention is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Mexitil:

Mexitil (1,893 reports)

Browse all side effects of Mexitil:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Urinary retention:

Urinary retention (1,570 drugs)

Browse all the conditions that are associated with Urinary retention:

Urinary retention (1,740 conditions)

Related publications that referenced our studies

Schattner A, Al-Bewerat A, "Levetiracetam (Keppra), urinary retention and literature search", A fatty cause of renal failure; what is your diagnosis?, 2016 Oct .
Schattner A, Al-Bewerat A, "Levetiracetam (Keppra), urinary retention and literature search", A fatty cause of renal failure; what is your diagnosis?, 2016 Oct .

How the study uses the data?

The study uses data from the FDA. It is based on mexiletine hydrochloride (the active ingredients of Mexitil) and Mexitil (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.