Miralax and Rectocele - a phase IV clinical study of FDA data

Summary:

Rectocele is reported as a side effect among people who take Miralax (polyethylene glycol 3350), especially for people who are 50-59 old, have been taking the drug for 6 - 12 months also take Neurontin, and have Breast cancer.

The phase IV clinical study analyzes which people have Rectocele when taking Miralax. It is created by eHealthMe based on reports of 80,819 people who have side effects when taking Miralax from the FDA, and is updated regularly.

What is Miralax?

Miralax has active ingredients of polyethylene glycol 3350. It is often used in constipation. eHealthMe is studying from 81,754 Miralax users. Check the latest studies of Miralax.

What is Rectocele?

Rectocele (a bulging of the front wall of the rectum into the back wall of the vagina) is found to be associated with 299 drugs and 319 conditions by eHealthMe. Check the latest studies of Rectocele.



On Jul, 13, 2026

80,819 people reported to have side effects when taking Miralax.
Among them, 30 people (0.04%) have Rectocele.

Could Miralax cause Rectocele?

Among these 30 people:

How long have people been on Miralax when they have Rectocele? *

  • < 1 month: 0.0 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 100 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the age of people who have Rectocele when taking Miralax? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 4 %
  • 50-59: 92 %
  • 60+: 4 %

What are other drugs people take besides Miralax? *

  1. Neurontin: 26 people, 86.67%
  2. Gabapentin: 25 people, 83.33%
  3. Atenolol: 24 people, 80.00%
  4. Furosemide: 24 people, 80.00%
  5. Zometa: 24 people, 80.00%
  6. Lexapro: 24 people, 80.00%
  7. Protonix: 23 people, 76.67%
  8. Zoloft: 23 people, 76.67%
  9. Zofran: 23 people, 76.67%
  10. Fentanyl: 23 people, 76.67%

What are other side effects people have besides Rectocele? *

  1. Joint Pain: 25 people, 83.33%
  2. Scar: 24 people, 80.00%
  3. Haemorrhoids (a swollen vein or group of veins in the region of the anus): 24 people, 80.00%
  4. Stress And Anxiety: 24 people, 80.00%
  5. Night Sweats (sweating in night): 24 people, 80.00%
  6. Emotional Distress: 24 people, 80.00%
  7. Injury: 24 people, 80.00%
  8. Cystocele (a condition that occurs when the tough fibrous wall between a woman's bladder and her vagina is torn by childbirth): 24 people, 80.00%
  9. Toothaches (tooth pain): 24 people, 80.00%
  10. Fever: 24 people, 80.00%

What are the existing conditions these people have? *

  1. Hypercalcaemia (elevated calcium (ca+) level in the blood): 21 people, 70.00%
  2. Breast Cancer: 21 people, 70.00%
  3. Breast Cancer Metastatic: 20 people, 66.67%
  4. Depression: 4 people, 13.33%
  5. Stress And Anxiety: 3 people, 10.00%
  6. Pain: 3 people, 10.00%
  7. Neoplasm Malignant (cancer tumour): 3 people, 10.00%
  8. Ovarian Cancer (cancer of ovary): 1 person, 3.33%
  9. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 1 person, 3.33%
  10. Migraine (headache): 1 person, 3.33%

* Approximation only. Some reports may have incomplete information.

Do you take Miralax and have Rectocele?

- Check whether Rectocele is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Miralax:

Rectocele treatments and more:

How severe was Rectocele and when was it recovered:

Expand to all the drugs that have ingredients of polyethylene glycol 3350:

Sub-studies by age:

0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Miralax:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Rectocele:

Browse all the conditions that are associated with Rectocele:


How the study uses the data?

The study uses data from the FDA. It is based on polyethylene glycol 3350 (the active ingredients of Miralax) and Miralax (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



Recent studies on eHealthMe: