Modafinil and Spinal pain - a phase IV clinical study of FDA data

Summary:

Spinal pain is reported as a side effect among people who take Modafinil (modafinil), especially for people who are female, 50-59 old, also take Benadryl, and have Rheumatoid arthritis.

The phase IV clinical study analyzes which people have Spinal pain when taking Modafinil. It is created by eHealthMe based on reports of 19,891 people who have side effects when taking Modafinil from the FDA, and is updated regularly.

What is Modafinil?

Modafinil has active ingredients of modafinil. It is often used in narcolepsy. eHealthMe is studying from 20,805 Modafinil users. Check the latest studies of Modafinil.

What is Spinal pain?

Spinal pain (pain in spine) is found to be associated with 786 drugs and 688 conditions by eHealthMe. Check the latest studies of Spinal pain.

On Jul, 17, 2026

19,891 people reported to have side effects when taking Modafinil.
Among them, 15 people (0.08%) have Spinal pain.

Among these 15 people:

What is the gender of people who have Spinal pain when taking Modafinil? *

female: 76.92 %
male: 23.08 %

What is the age of people who have Spinal pain when taking Modafinil? *

What are other drugs people take besides Modafinil? *

What are other side effects people have besides Spinal pain? *

Back Pain: 10 people, 66.67%
High Blood Pressure: 7 people, 46.67%
Fall: 7 people, 46.67%
Oxygen Saturation Decreased: 6 people, 40.00%
Blood Pressure Systolic Increased: 6 people, 40.00%
Spinal Compression Fracture (fracture due to spinal compression on bone): 6 people, 40.00%
Body Temperature Decreased: 6 people, 40.00%
Blood Pressure Systolic Abnormal: 6 people, 40.00%
Fatigue (feeling of tiredness): 5 people, 33.33%
Upper Limb Fracture: 5 people, 33.33%

What are the existing conditions these people have? *

Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 6 people, 40.00%
Pain: 3 people, 20.00%
Restless Leg Syndrome (a powerful urge to move your legs): 2 people, 13.33%
Muscle Spasms (muscle contraction): 2 people, 13.33%
Depression: 2 people, 13.33%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 2 people, 13.33%
Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 1 person, 6.67%
Osteoporosis Post-Menopausal (weak bone with possibility to break after stopped menstrual cycles): 1 person, 6.67%
Oral Herpes (viral infection of mouth): 1 person, 6.67%
Neuralgia (pain in one or more nerves): 1 person, 6.67%

* Approximation only. Some reports may have incomplete information.

Do you take Modafinil and have Spinal pain?

- Check whether Spinal pain is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Modafinil:

Modafinil (20,805 reports)

Spinal pain treatments and more:

Spinal pain (17,834 reports)

Browse all side effects of Modafinil:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Spinal pain:

Spinal pain (786 drugs)

Browse all the conditions that are associated with Spinal pain:

Spinal pain (688 conditions)

Related publications that referenced our studies

Lopes E, Pereira D, da Silva Behrens NS, de Almeida Fonseca H, Calvancanti PO, de Araújo Lima TF, Pradella-Hallinan M, Castro J, Tufik S, Coelho FM, "Cataplexy as a side effect of modafinil in a patient without narcolepsy", Sleep Science, 2014 Mar .
Lopes E, Pereira D, da Silva Behrens NS, de Almeida Fonseca H, Calvancanti PO, de Araújo Lima TF, Pradella-Hallinan M, Castro J, Tufik S, Coelho FM, "Cataplexy as a side effect of modafinil in a patient without narcolepsy", Sleep Science, 2014 Mar .

How the study uses the data?

The study uses data from the FDA. It is based on modafinil (the active ingredients of Modafinil) and Modafinil (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.