Moduretic 5-50 and Myopathy - a phase IV clinical study of FDA data

Summary:

Myopathy is reported as a side effect among people who take Moduretic 5-50 (amiloride hydrochloride; hydrochlorothiazide), especially for people who are female, 60+ old, also take Zocor, and have Device related infection.

The phase IV clinical study analyzes which people have Myopathy when taking Moduretic 5-50. It is created by eHealthMe based on reports of 3,193 people who have side effects when taking Moduretic 5-50 from the FDA, and is updated regularly.

What is Moduretic 5-50?

Moduretic 5-50 has active ingredients of amiloride hydrochloride; hydrochlorothiazide. It is often used in high blood pressure. eHealthMe is studying from 3,224 Moduretic 5-50 users. Check the latest studies of Moduretic 5-50.

What is Myopathy?

Myopathy (a muscular disease in which the muscle fibres do not function) is found to be associated with 823 drugs and 1,015 conditions by eHealthMe. Check the latest studies of Myopathy.

On Jul, 15, 2026

3,193 people reported to have side effects when taking Moduretic 5-50.
Among them, 21 people (0.66%) have Myopathy.

Among these 21 people:

What is the gender of people who have Myopathy when taking Moduretic 5-50? *

female: 100 %
male: 0.0 %

What is the age of people who have Myopathy when taking Moduretic 5-50? *

What are other drugs people take besides Moduretic 5-50? *

Zocor: 18 people, 85.71%
Acetaminophen: 11 people, 52.38%
Lorazepam: 11 people, 52.38%
Folic Acid: 11 people, 52.38%
Flurazepam Hydrochloride: 11 people, 52.38%
Duloxetine Hydrochloride: 11 people, 52.38%
Diclofenac: 11 people, 52.38%
Dexchlorpheniramine Maleate: 11 people, 52.38%
Cubicin: 11 people, 52.38%
Lipitor: 10 people, 47.62%

What are other side effects people have besides Myopathy? *

Hyperlipidaemia (presence of excess lipids in the blood): 9 people, 42.86%
Metastatic Neoplasm (spreadable cancer tumour): 9 people, 42.86%
Osteoporosis (bones weak and more likely to break): 9 people, 42.86%
Osteopenia (a condition where bone mineral density is lower than normal): 9 people, 42.86%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 9 people, 42.86%
Rib Fracture: 9 people, 42.86%
Cholecystitis (infection of gallbladder): 9 people, 42.86%
Scoliosis (a medical condition in which a person's spine is curved from side to side): 9 people, 42.86%
Stress And Anxiety: 9 people, 42.86%
Pain In Jaw: 9 people, 42.86%

What are the existing conditions these people have? *

Device Related Infection: 11 people, 52.38%
Oesophageal Disorder (disease of oesophagus): 1 person, 4.76%
Metabolic Disorder (an abnormal function and pattern of body fat. insulin resistance refers to the diminished ability of cells to respond to the action of insulin in promoting the transport of the sugar glucose, from blood into muscles and other tissues): 1 person, 4.76%

* Approximation only. Some reports may have incomplete information.

Do you take Moduretic 5-50 and have Myopathy?

- Check whether Myopathy is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Moduretic 5-50:

Moduretic 5-50 (3,224 reports)

Myopathy treatments and more:

Myopathy (12,767 reports)

How severe was Myopathy and when was it recovered:

Myopathy in Moduretic 5-50

Expand to all the drugs that have ingredients of amiloride hydrochloride; hydrochlorothiazide:

Myopathy and drugs with ingredients of amiloride hydrochloride; hydrochlorothiazide (14 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Moduretic 5-50:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Myopathy:

Myopathy (823 drugs)

Browse all the conditions that are associated with Myopathy:

Myopathy (1,015 conditions)

Related publications that referenced our studies

Das S, Anand Ramasamy SD, Mondal S, "An unusual case of glipizide-induced proximal myopathy", Journal of pharmacology & pharmacotherapeutics, 2016 Jan .
Das S, Anand Ramasamy SD, Mondal S, "An unusual case of glipizide-induced proximal myopathy", Journal of pharmacology & pharmacotherapeutics, 2016 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on amiloride hydrochloride; hydrochlorothiazide (the active ingredients of Moduretic 5-50) and Moduretic 5-50 (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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