Morphine and Hypercoagulation - a phase IV clinical study of FDA data

Summary:

Hypercoagulation is reported as a side effect among people who take Morphine (morphine sulfate), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Zometa, and have Metastases to bone.

The phase IV clinical study analyzes which people have Hypercoagulation when taking Morphine. It is created by eHealthMe based on reports of 180,723 people who have side effects when taking Morphine from the FDA, and is updated regularly.

What is Morphine?

Morphine has active ingredients of morphine sulfate. It is often used in pain. eHealthMe is studying from 182,913 Morphine users. Check the latest studies of Morphine.

What is Hypercoagulation?

Hypercoagulation (increased tendency for clotting of the blood) is found to be associated with 404 drugs and 536 conditions by eHealthMe. Check the latest studies of Hypercoagulation.

On May, 01, 2026

180,723 people reported to have side effects when taking Morphine.
Among them, 38 people (0.02%) have Hypercoagulation.

Among these 38 people:

How long have people been on Morphine when they have Hypercoagulation? *

What is the gender of people who have Hypercoagulation when taking Morphine? *

female: 75.68 %
male: 24.32 %

What is the age of people who have Hypercoagulation when taking Morphine? *

What are other drugs people take besides Morphine? *

What are other side effects people have besides Hypercoagulation? *

Gastrointestinal Haemorrhage (bleeding gastrointestinal tract): 23 people, 60.53%
Fatigue (feeling of tiredness): 21 people, 55.26%
Anaemia (lack of blood): 21 people, 55.26%
Dyspnea (difficult or laboured breathing): 21 people, 55.26%
Joint Pain: 21 people, 55.26%
Deep Venous Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 20 people, 52.63%
Pneumothorax (the presence of air or gas in the cavity between the lungs and the chest wall, causing collapse of the lung): 20 people, 52.63%
Tenderness (pain or discomfort when an affected area is touched): 20 people, 52.63%
Impaired Healing: 19 people, 50.00%
Osteoporosis (bones weak and more likely to break): 19 people, 50.00%

What are the existing conditions these people have? *

Metastases To Bone (cancer spreads to bone): 18 people, 47.37%
Multiple Myeloma (cancer of the plasma cells): 4 people, 10.53%
Diabetes: 3 people, 7.89%
Stress And Anxiety: 2 people, 5.26%
Sedation: 2 people, 5.26%
Renal Disorder (kidney disease): 2 people, 5.26%
Deep Venous Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 2 people, 5.26%
Breast Cancer: 2 people, 5.26%
Blood Uric Acid Increased: 1 person, 2.63%
Depression: 1 person, 2.63%

* Approximation only. Some reports may have incomplete information.

Do you take Morphine and have Hypercoagulation?

- Check whether Hypercoagulation is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Morphine:

Morphine (182,913 reports)

Browse all side effects of Morphine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hypercoagulation:

Hypercoagulation (404 drugs)

Browse all the conditions that are associated with Hypercoagulation:

Hypercoagulation (536 conditions)

Related publications that referenced our studies

Rasmy A, Rahal M, Kisana M, Ahmad S, Salah A, "Morphine induced thrombocytopenia: A case report", Journal of Case Reports and Images in Oncology, 2015 Dec .
Rasmy A, Rahal M, Kisana M, Ahmad S, Salah A, "Morphine induced thrombocytopenia: A case report", Journal of Case Reports and Images in Oncology, 2015 Dec .

How the study uses the data?

The study uses data from the FDA. It is based on morphine sulfate (the active ingredients of Morphine) and Morphine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.