Ms contin and Restless leg syndrome - a phase IV clinical study of FDA data

Summary:

Restless leg syndrome is reported as a side effect among people who take Ms contin (morphine sulfate), especially for people who are male, 40-49 old, also take Oxycontin, and have Insomnia.

The phase IV clinical study analyzes which people have Restless leg syndrome when taking Ms contin. It is created by eHealthMe based on reports of 68,873 people who have side effects when taking Ms contin from the FDA, and is updated regularly.

What is Ms contin?

Ms contin has active ingredients of morphine sulfate. It is often used in pain. eHealthMe is studying from 69,289 Ms contin users. Check the latest studies of Ms contin.

What is Restless leg syndrome?

Restless leg syndrome (a powerful urge to move your legs) is found to be associated with 1,246 drugs and 1,935 conditions by eHealthMe. Check the latest studies of Restless leg syndrome.

On Jul, 26, 2026

68,873 people reported to have side effects when taking Ms contin.
Among them, 57 people (0.08%) have Restless leg syndrome.

Could Ms contin cause Restless leg syndrome?

Among these 57 people:

What is the gender of people who have Restless leg syndrome when taking Ms contin? *

female: 49.12 %
male: 50.88 %

What is the age of people who have Restless leg syndrome when taking Ms contin? *

What are other drugs people take besides Ms contin? *

What are other side effects people have besides Restless leg syndrome? *

Stress And Anxiety: 30 people, 52.63%
Nausea (feeling of having an urge to vomit): 29 people, 50.88%
Drug Dependence: 26 people, 45.61%
Pain In Extremity: 23 people, 40.35%
Fatigue (feeling of tiredness): 20 people, 35.09%
Rectal Haemorrhage (bleeding from anus): 19 people, 33.33%
Dyspnea (difficult or laboured breathing): 18 people, 31.58%
High Blood Pressure: 18 people, 31.58%
Constipation: 18 people, 31.58%
Nausea And Vomiting: 18 people, 31.58%

What are the existing conditions these people have? *

Insomnia (sleeplessness): 4 people, 7.02%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 3 people, 5.26%
Hyperlipidaemia (presence of excess lipids in the blood): 3 people, 5.26%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 3 people, 5.26%
Neuralgia (pain in one or more nerves): 3 people, 5.26%
Faeces Hard: 3 people, 5.26%
Constipation: 3 people, 5.26%
Impaired Gastric Emptying: 3 people, 5.26%
Pain In Extremity: 2 people, 3.51%
Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 2 people, 3.51%

* Approximation only. Some reports may have incomplete information.

Do you take Ms contin and have Restless leg syndrome?

- Check whether Restless leg syndrome is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Ms contin:

Ms contin (69,289 reports)

Browse all side effects of Ms contin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Restless leg syndrome:

Restless leg syndrome (1,246 drugs)

Browse all the conditions that are associated with Restless leg syndrome:

Restless leg syndrome (1,935 conditions)

Related publications that referenced our studies

Rasmy A, Rahal M, Kisana M, Ahmad S, Salah A, "Morphine induced thrombocytopenia: A case report", Journal of Case Reports and Images in Oncology, 2015 Dec .
Rasmy A, Rahal M, Kisana M, Ahmad S, Salah A, "Morphine induced thrombocytopenia: A case report", Journal of Case Reports and Images in Oncology, 2015 Dec .

How the study uses the data?

The study uses data from the FDA. It is based on morphine sulfate (the active ingredients of Ms contin) and Ms contin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.