Msm and Atrial fibrillation/flutter - a phase IV clinical study of FDA data

Summary:

Atrial fibrillation/flutter is reported as a side effect among people who take Msm (methylsulfonylmethane), especially for people who are female, 60+ old, also take Vitamin C, and have Primary pulmonary hypertension.

The phase IV clinical study analyzes which people have Atrial fibrillation/flutter when taking Msm. It is created by eHealthMe based on reports of 978 people who have side effects when taking Msm from the FDA, and is updated regularly.

What is Msm?

Msm has active ingredients of methylsulfonylmethane. It is often used in joint pain. eHealthMe is studying from 1,210 Msm users. Check the latest studies of Msm.

What is Atrial fibrillation/flutter?

Atrial fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles) is found to be associated with 2,366 drugs and 3,840 conditions by eHealthMe. Check the latest studies of Atrial fibrillation/flutter.

On Jul, 06, 2026

978 people reported to have side effects when taking Msm.
Among them, 14 people (1.43%) have Atrial fibrillation/flutter.

Could Msm cause Atrial fibrillation/flutter?

Among these 14 people:

What is the gender of people who have Atrial fibrillation/flutter when taking Msm? *

female: 58.33 %
male: 41.67 %

What is the age of people who have Atrial fibrillation/flutter when taking Msm? *

What are other drugs people take besides Msm? *

What are other side effects people have besides Atrial fibrillation/flutter? *

Nosebleed (bleeding from nose): 4 people, 28.57%
Hypotension (abnormally low blood pressure): 4 people, 28.57%
Muscle Spasms (muscle contraction): 3 people, 21.43%
Stress And Anxiety: 3 people, 21.43%
Presyncope: 3 people, 21.43%
Arrhythmias (irregular heartbeat): 3 people, 21.43%
Weakness: 3 people, 21.43%
Cardioversion: 3 people, 21.43%
Enlarged Heart: 2 people, 14.29%
Nausea (feeling of having an urge to vomit): 2 people, 14.29%

What are the existing conditions these people have? *

Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 5 people, 35.71%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 2 people, 14.29%
Idiopathic Thrombocytopenic Purpura (bleeding disorder in which the immune system destroys platelets, which are necessary for normal blood clotting): 2 people, 14.29%
Urinary Tract Infection: 1 person, 7.14%
Renal Disorder (kidney disease): 1 person, 7.14%
Precancerous Skin Lesion: 1 person, 7.14%
Parkinson's Disease: 1 person, 7.14%
Neuropathy Peripheral (surface nerve damage): 1 person, 7.14%
Multiple Myeloma (cancer of the plasma cells): 1 person, 7.14%
Lambert-Eaton Syndrome (this means your immune system mistakenly targets healthy cells and tissues in the body): 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

Do you take Msm and have Atrial fibrillation/flutter?

- Check whether Atrial fibrillation/flutter is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Msm:

Msm (1,210 reports)

Browse all side effects of Msm:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Atrial fibrillation/flutter:

Atrial fibrillation/flutter (2,366 drugs)

Browse all the conditions that are associated with Atrial fibrillation/flutter:

Atrial fibrillation/flutter (3,840 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on methylsulfonylmethane (the active ingredients of Msm) and Msm (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.