Naloxone and Fainting - a phase IV clinical study of FDA data

Summary:

Fainting is reported as a side effect among people who take Naloxone (naloxone hydrochloride), especially for people who are female, 60+ old, also take Apixaban, and have Pain.

The phase IV clinical study analyzes which people have Fainting when taking Naloxone. It is created by eHealthMe based on reports of 6,366 people who have side effects when taking Naloxone from the FDA, and is updated regularly.

What is Naloxone?

Naloxone has active ingredients of naloxone hydrochloride. eHealthMe is studying from 6,425 Naloxone users. Check the latest studies of Naloxone.

What is Fainting?

Fainting (loss of consciousness and postural tone) is found to be associated with 2,456 drugs and 3,547 conditions by eHealthMe. Check the latest studies of Fainting.



On Jul, 13, 2026

6,366 people reported to have side effects when taking Naloxone.
Among them, 32 people (0.5%) have Fainting.

Could Naloxone cause Fainting?

Among these 32 people:

What is the gender of people who have Fainting when taking Naloxone? *

  • female: 54.84 %
  • male: 45.16 %

What is the age of people who have Fainting when taking Naloxone? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 3.33 %
  • 40-49: 13.33 %
  • 50-59: 13.33 %
  • 60+: 70.0 %

What are other drugs people take besides Naloxone? *

  1. Lyrica: 5 people, 15.62%
  2. Apixaban: 5 people, 15.62%
  3. Bactrim: 3 people, 9.38%
  4. Pantoprazole: 3 people, 9.38%
  5. Allopurinol: 3 people, 9.38%
  6. Tamsulosin: 3 people, 9.38%
  7. Omeprazole: 2 people, 6.25%
  8. Fluconazole: 2 people, 6.25%
  9. Colecalciferol: 2 people, 6.25%
  10. Carfilzomib: 2 people, 6.25%

What are other side effects people have besides Fainting? *

  1. General Physical Health Deterioration (weak health status): 9 people, 28.12%
  2. Fatigue (feeling of tiredness): 7 people, 21.88%
  3. Dyspnea (difficult or laboured breathing): 7 people, 21.88%
  4. Hypotension (abnormally low blood pressure): 6 people, 18.75%
  5. Nausea (feeling of having an urge to vomit): 6 people, 18.75%
  6. Dizziness: 6 people, 18.75%
  7. Cough: 5 people, 15.62%
  8. Fall: 5 people, 15.62%
  9. Arrhythmias (irregular heartbeat): 5 people, 15.62%
  10. Bradycardia (abnormally slow heart action): 5 people, 15.62%

What are the existing conditions these people have? *

  1. Pain: 3 people, 9.38%
  2. Back Pain: 2 people, 6.25%
  3. Prostate Cancer Metastatic: 2 people, 6.25%
  4. Cardiogenic Shock (inadequate circulation of blood): 2 people, 6.25%
  5. Neuralgia (pain in one or more nerves): 2 people, 6.25%
  6. Dyspnea (difficult or laboured breathing): 2 people, 6.25%
  7. Seizures (abnormal excessive or synchronous neuronal activity in the brain): 2 people, 6.25%
  8. Hepatitis C: 1 person, 3.12%
  9. Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 1 person, 3.12%
  10. Constipation: 1 person, 3.12%

* Approximation only. Some reports may have incomplete information.

Do you take Naloxone and have Fainting?

- Check whether Fainting is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Naloxone:

Fainting treatments and more:

How severe was Fainting and when was it recovered:

Expand to all the drugs that have ingredients of naloxone hydrochloride:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Naloxone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Fainting:

Browse all the conditions that are associated with Fainting:


How the study uses the data?

The study uses data from the FDA. It is based on naloxone hydrochloride (the active ingredients of Naloxone) and Naloxone (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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