Naproxen and Bladder dysfunction - a phase IV clinical study of FDA data

Summary:

Bladder dysfunction is reported as a side effect among people who take Naproxen (naproxen), especially for people who are female, 50-59 old, have been taking the drug for < 1 month also take Cymbalta, and have Fibromyalgia.

The phase IV clinical study analyzes which people have Bladder dysfunction when taking Naproxen. It is created by eHealthMe based on reports of 68,942 people who have side effects when taking Naproxen from the FDA, and is updated regularly.

What is Naproxen?

Naproxen has active ingredients of naproxen. It is often used in pain. eHealthMe is studying from 72,032 Naproxen users. Check the latest studies of Naproxen.

What is Bladder dysfunction?

Bladder dysfunction is found to be associated with 241 drugs and 274 conditions by eHealthMe. Check the latest studies of Bladder dysfunction.

On May, 24, 2026

68,942 people reported to have side effects when taking Naproxen.
Among them, 15 people (0.02%) have Bladder dysfunction.

Could Naproxen cause Bladder dysfunction?

Among these 15 people:

How long have people been on Naproxen when they have Bladder dysfunction? *

What is the gender of people who have Bladder dysfunction when taking Naproxen? *

female: 73.33 %
male: 26.67 %

What is the age of people who have Bladder dysfunction when taking Naproxen? *

What are other drugs people take besides Naproxen? *

What are other side effects people have besides Bladder dysfunction? *

Urinary Tract Infection: 10 people, 66.67%
Fall: 10 people, 66.67%
Multiple Sclerosis Relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 7 people, 46.67%
Progressive Multifocal Leukoencephalopathy (rapidly progressive neuromuscular disease caused by opportunistic infection of brain cells): 7 people, 46.67%
Pneumonia Aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree): 5 people, 33.33%
Headache (pain in head): 4 people, 26.67%
Respiratory Acidosis (respiratory failure or ventilatory failure, causes the ph of blood and other bodily fluids to decrease): 4 people, 26.67%
Dyspnea (difficult or laboured breathing): 4 people, 26.67%
Femoral Artery Occlusion (obstruction in artery of femur): 3 people, 20.00%
Osteoarthritis (a joint disease caused by cartilage loss in a joint): 3 people, 20.00%

What are the existing conditions these people have? *

Sleep Disorder: 7 people, 46.67%
Restless Leg Syndrome (a powerful urge to move your legs): 7 people, 46.67%
Neurogenic Bladder (the normal function of the bladder is to store and empty urine in a coordinated, controlled fashion): 7 people, 46.67%
Muscle Spasticity (tight or stiff muscles and an inability to control those muscles): 7 people, 46.67%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 7 people, 46.67%
Migraine (headache): 7 people, 46.67%
Stress And Anxiety: 7 people, 46.67%
Cystitis Interstitial (unknown cause characterized by bladder pain): 7 people, 46.67%
Depression: 7 people, 46.67%
Fibromyalgia (a long-term condition which causes pain all over the body): 7 people, 46.67%

* Approximation only. Some reports may have incomplete information.

Do you take Naproxen and have Bladder dysfunction?

- Check whether Bladder dysfunction is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Naproxen:

Naproxen (72,032 reports)

Browse all side effects of Naproxen:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Bladder dysfunction:

Bladder dysfunction (241 drugs)

Browse all the conditions that are associated with Bladder dysfunction:

Bladder dysfunction (274 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on naproxen (the active ingredients of Naproxen) and Naproxen (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.