Naproxen and Defaecation urgency - a phase IV clinical study of FDA data

Summary:

Defaecation urgency is reported as a side effect among people who take Naproxen (naproxen), especially for people who are female, 50-59 old, also take Prilosec, and have Ulcerative colitis.

The phase IV clinical study analyzes which people have Defaecation urgency when taking Naproxen. It is created by eHealthMe based on reports of 68,942 people who have side effects when taking Naproxen from the FDA, and is updated regularly.

What is Naproxen?

Naproxen has active ingredients of naproxen. It is often used in pain. eHealthMe is studying from 72,033 Naproxen users. Check the latest studies of Naproxen.

What is Defaecation urgency?

Defaecation urgency (a sudden compelling urge to defecate) is found to be associated with 537 drugs and 518 conditions by eHealthMe. Check the latest studies of Defaecation urgency.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 25, 2026

68,942 people reported to have side effects when taking Naproxen.
Among them, 11 people (0.02%) have Defaecation urgency.

Could Naproxen cause Defaecation urgency?

Among these 11 people:

What is the gender of people who have Defaecation urgency when taking Naproxen? *

female: 100 %
male: 0.0 %

What is the age of people who have Defaecation urgency when taking Naproxen? *

What are other drugs people take besides Naproxen? *

What are other side effects people have besides Defaecation urgency? *

Diarrhea: 6 people, 54.55%
Weight Decreased: 5 people, 45.45%
Fatigue (feeling of tiredness): 4 people, 36.36%
Malaise (a feeling of general discomfort or uneasiness): 4 people, 36.36%
Abdominal Pain: 4 people, 36.36%
Fall: 4 people, 36.36%
Abdominal Discomfort: 3 people, 27.27%
Nausea And Vomiting: 3 people, 27.27%
Joint Pain: 3 people, 27.27%
Weight Increased: 3 people, 27.27%

What are the existing conditions these people have? *

Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 3 people, 27.27%
Ovarian Cancer (cancer of ovary): 2 people, 18.18%
Neuropathy Peripheral (surface nerve damage): 2 people, 18.18%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1 person, 9.09%
Quit Smoking: 1 person, 9.09%
Migraine (headache): 1 person, 9.09%
Diabetes: 1 person, 9.09%
Depression: 1 person, 9.09%
Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 1 person, 9.09%
Birth Control: 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Naproxen and have Defaecation urgency?

- Check whether Defaecation urgency is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Naproxen:

Naproxen (72,033 reports)

Browse all side effects of Naproxen:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Defaecation urgency:

Defaecation urgency (537 drugs)

Browse all the conditions that are associated with Defaecation urgency:

Defaecation urgency (518 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on naproxen (the active ingredients of Naproxen) and Naproxen (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.