Naproxen and Demyelination - a phase IV clinical study of FDA data

Summary:

Demyelination is reported as a side effect among people who take Naproxen (naproxen), especially for people who are female, 10-19 old, also take Enbrel, and have Rheumatoid arthritis.

The phase IV clinical study analyzes which people have Demyelination when taking Naproxen. It is created by eHealthMe based on reports of 68,942 people who have side effects when taking Naproxen from the FDA, and is updated regularly.

What is Naproxen?

Naproxen has active ingredients of naproxen. It is often used in pain. eHealthMe is studying from 72,032 Naproxen users. Check the latest studies of Naproxen.

What is Demyelination?

Demyelination (loss of the myelin covering of some nerve fibres resulting in their impaired function) is found to be associated with 464 drugs and 669 conditions by eHealthMe. Check the latest studies of Demyelination.

On Jul, 11, 2026

68,942 people reported to have side effects when taking Naproxen.
Among them, 70 people (0.1%) have Demyelination.

Among these 70 people:

What is the gender of people who have Demyelination when taking Naproxen? *

female: 67.21 %
male: 32.79 %

What is the age of people who have Demyelination when taking Naproxen? *

What are other drugs people take besides Naproxen? *

Enbrel: 28 people, 40.00%
Methotrexate: 22 people, 31.43%
Folic Acid: 16 people, 22.86%
Prednisone: 16 people, 22.86%
Cymbalta: 15 people, 21.43%
Esomeprazole Magnesium: 14 people, 20.00%
Zopiclone: 13 people, 18.57%
Prevacid: 13 people, 18.57%
Aspirin: 13 people, 18.57%
Atenolol: 13 people, 18.57%

What are other side effects people have besides Demyelination? *

Progressive Multifocal Leukoencephalopathy (rapidly progressive neuromuscular disease caused by opportunistic infection of brain cells): 22 people, 31.43%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 22 people, 31.43%
Fatigue (feeling of tiredness): 21 people, 30.00%
Drug Ineffective: 21 people, 30.00%
Neuropathy Peripheral (surface nerve damage): 18 people, 25.71%
Fall: 17 people, 24.29%
Joint Pain: 17 people, 24.29%
Post-Traumatic Stress Disorder: 16 people, 22.86%
Dizziness: 15 people, 21.43%
Weakness: 15 people, 21.43%

What are the existing conditions these people have? *

Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 14 people, 20.00%
Juvenile Rheumatoid Arthritis (joint inflammation in children due to systemic disease): 11 people, 15.71%
Ankylosing Spondylitis (type of arthritis affecting the spine): 7 people, 10.00%
Sleep Disorder: 6 people, 8.57%
Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 6 people, 8.57%
Hypersensitivity: 6 people, 8.57%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 4 people, 5.71%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 3 people, 4.29%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 3 people, 4.29%
Gout (uric acid crystals building up in the body): 3 people, 4.29%

* Approximation only. Some reports may have incomplete information.

Do you take Naproxen and have Demyelination?

- Check whether Demyelination is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Naproxen:

Naproxen (72,032 reports)

Demyelination treatments and more:

Demyelination (5,739 reports)

Browse all side effects of Naproxen:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Demyelination:

Demyelination (464 drugs)

Browse all the conditions that are associated with Demyelination:

Demyelination (669 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on naproxen (the active ingredients of Naproxen) and Naproxen (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.