Naproxen and Gallbladder disease - a phase IV clinical study of FDA data

Summary:

Gallbladder disease is reported as a side effect among people who take Naproxen (naproxen), especially for people who are female, 20-29 old, have been taking the drug for 1 - 6 months also take Yasmin, and have Birth control.

The phase IV clinical study analyzes which people have Gallbladder disease when taking Naproxen. It is created by eHealthMe based on reports of 68,942 people who have side effects when taking Naproxen from the FDA, and is updated regularly.

What is Naproxen?

Naproxen has active ingredients of naproxen. It is often used in pain. eHealthMe is studying from 72,032 Naproxen users. Check the latest studies of Naproxen.

What is Gallbladder disease?

Gallbladder disease is found to be associated with 445 drugs and 1,000 conditions by eHealthMe. Check the latest studies of Gallbladder disease.

On Jul, 12, 2026

68,942 people reported to have side effects when taking Naproxen.
Among them, 72 people (0.1%) have Gallbladder disease.

Could Naproxen cause Gallbladder disease?

Among these 72 people:

How long have people been on Naproxen when they have Gallbladder disease? *

What is the gender of people who have Gallbladder disease when taking Naproxen? *

female: 100 %
male: 0.0 %

What is the age of people who have Gallbladder disease when taking Naproxen? *

What are other drugs people take besides Naproxen? *

Yasmin: 43 people, 59.72%
Yaz: 31 people, 43.06%
Ibuprofen: 21 people, 29.17%
Albuterol: 15 people, 20.83%
Drospirenone And Ethinyl Estradiol: 13 people, 18.06%
Amoxicillin: 12 people, 16.67%
Prednisone: 11 people, 15.28%
Protonix: 10 people, 13.89%
Zofran: 10 people, 13.89%
Hydrocodone Bitartrate And Acetaminophen: 9 people, 12.50%

What are other side effects people have besides Gallbladder disease? *

Gallstones (stone formation by bile component): 49 people, 68.06%
Abdominal Pain Upper: 34 people, 47.22%
Nausea (feeling of having an urge to vomit): 32 people, 44.44%
Cholecystitis Chronic (long lasting infection of gallbladder): 28 people, 38.89%
Abdominal Pain: 18 people, 25.00%
Gallbladder Disorder: 15 people, 20.83%
Nausea And Vomiting: 15 people, 20.83%
Cholecystitis (infection of gallbladder): 15 people, 20.83%
Stress And Anxiety: 14 people, 19.44%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 13 people, 18.06%

What are the existing conditions these people have? *

Birth Control: 22 people, 30.56%
Premenstrual Syndrome: 12 people, 16.67%
High Blood Pressure: 11 people, 15.28%
Nausea (feeling of having an urge to vomit): 9 people, 12.50%
Stress And Anxiety: 9 people, 12.50%
Asthma: 9 people, 12.50%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 8 people, 11.11%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 8 people, 11.11%
Migraine (headache): 7 people, 9.72%
Weight Loss: 7 people, 9.72%

* Approximation only. Some reports may have incomplete information.

Do you take Naproxen and have Gallbladder disease?

- Check whether Gallbladder disease is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Naproxen:

Naproxen (72,032 reports)

Browse all side effects of Naproxen:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Gallbladder disease:

Gallbladder disease (445 drugs)

Browse all the conditions that are associated with Gallbladder disease:

Gallbladder disease (1,000 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on naproxen (the active ingredients of Naproxen) and Naproxen (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.