Naproxen and Sinus pain - a phase IV clinical study of FDA data

Summary:

Sinus pain is reported as a side effect among people who take Naproxen (naproxen), especially for people who are female, 50-59 old, also take Folic Acid, and have Rheumatoid arthritis.

The phase IV clinical study analyzes which people have Sinus pain when taking Naproxen. It is created by eHealthMe based on reports of 68,942 people who have side effects when taking Naproxen from the FDA, and is updated regularly.

What is Naproxen?

Naproxen has active ingredients of naproxen. It is often used in pain. eHealthMe is studying from 72,032 Naproxen users. Check the latest studies of Naproxen.

What is Sinus pain?

Sinus pain is found to be associated with 368 drugs and 315 conditions by eHealthMe. Check the latest studies of Sinus pain.

On Jul, 06, 2026

68,942 people reported to have side effects when taking Naproxen.
Among them, 38 people (0.06%) have Sinus pain.

Among these 38 people:

What is the gender of people who have Sinus pain when taking Naproxen? *

female: 93.75 %
male: 6.25 %

What is the age of people who have Sinus pain when taking Naproxen? *

What are other drugs people take besides Naproxen? *

Methotrexate: 20 people, 52.63%
Folic Acid: 20 people, 52.63%
Acetaminophen: 19 people, 50.00%
Altace: 19 people, 50.00%
Methylprednisolone: 19 people, 50.00%
Citalopram Hydrobromide: 18 people, 47.37%
Rosuvastatin Calcium: 18 people, 47.37%
Diphenhydramine Hydrochloride: 18 people, 47.37%
Aspirin: 18 people, 47.37%
Morphine Sulfate: 16 people, 42.11%

What are other side effects people have besides Sinus pain? *

Fatigue (feeling of tiredness): 34 people, 89.47%
Joint Pain: 31 people, 81.58%
Nasal Congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels): 26 people, 68.42%
Weight Increased: 24 people, 63.16%
Nasopharyngitis (inflammation of the nasopharynx): 21 people, 55.26%
Drug Ineffective: 20 people, 52.63%
Throat Irritation: 19 people, 50.00%
Infusion Related Reaction: 19 people, 50.00%
Foot Fracture: 19 people, 50.00%
Joint Swelling: 19 people, 50.00%

What are the existing conditions these people have? *

Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 20 people, 52.63%
Urinary Tract Infection: 5 people, 13.16%
Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 5 people, 13.16%
Juvenile Rheumatoid Arthritis (joint inflammation in children due to systemic disease): 5 people, 13.16%
Cellulitis (infection under the skin): 5 people, 13.16%
Systemic Lupus Erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue): 3 people, 7.89%
Sinusitis (inflammation of sinus): 3 people, 7.89%
Neuralgia (pain in one or more nerves): 3 people, 7.89%
Lower Respiratory Tract Infection: 3 people, 7.89%
Wheezing (a high-pitched whistling sound made while you breath): 1 person, 2.63%

* Approximation only. Some reports may have incomplete information.

Do you take Naproxen and have Sinus pain?

- Check whether Sinus pain is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Naproxen:

Naproxen (72,032 reports)

Sinus pain treatments and more:

Sinus pain (3,575 reports)

Browse all side effects of Naproxen:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Sinus pain:

Sinus pain (368 drugs)

Browse all the conditions that are associated with Sinus pain:

Sinus pain (315 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on naproxen (the active ingredients of Naproxen) and Naproxen (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.