Naropin and Acute kidney failure - a phase IV clinical study of FDA data

Summary:

Acute kidney failure is reported as a side effect among people who take Naropin (ropivacaine hydrochloride monohydrate), especially for people who are female, 50-59 old, have been taking the drug for < 1 month also take Neurontin, and have Anaesthesia.

The phase IV clinical study analyzes which people have Acute kidney failure when taking Naropin. It is created by eHealthMe based on reports of 1,155 people who have side effects when taking Naropin from the FDA, and is updated regularly.

What is Naropin?

Naropin has active ingredients of ropivacaine hydrochloride monohydrate. eHealthMe is studying from 1,156 Naropin users. Check the latest studies of Naropin.

What is Acute kidney failure?

Acute kidney failure is found to be associated with 2,836 drugs and 4,496 conditions by eHealthMe. Check the latest studies of Acute kidney failure.



On Aug, 05, 2026

1,155 people reported to have side effects when taking Naropin.
Among them, 64 people (5.54%) have Acute kidney failure.

Could Naropin cause Acute kidney failure?

Among these 64 people:

How long have people been on Naropin when they have Acute kidney failure? *

  • < 1 month: 94.34 %
  • 1 - 6 months: 5.66 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Acute kidney failure when taking Naropin? *

  • female: 92.19 %
  • male: 7.81 %

What is the age of people who have Acute kidney failure when taking Naropin? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 8.06 %
  • 20-29: 0.0 %
  • 30-39: 16.13 %
  • 40-49: 16.13 %
  • 50-59: 37.1 %
  • 60+: 20.97 %

What are other drugs people take besides Naropin? *

  1. Neurontin: 53 people, 82.81%
  2. Lovenox: 46 people, 71.88%
  3. Droperidol: 41 people, 64.06%
  4. Augmentin '125': 40 people, 62.50%
  5. Propofol: 40 people, 62.50%
  6. Betadine: 38 people, 59.38%
  7. Sufenta Preservative Free: 28 people, 43.75%
  8. Ultiva: 24 people, 37.50%
  9. Morphine: 24 people, 37.50%
  10. Ketamine Hcl: 23 people, 35.94%

What are other side effects people have besides Acute kidney failure? *

  1. Haematuria (presence of blood in urine): 36 people, 56.25%
  2. Urine Output - Decreased: 34 people, 53.12%
  3. Lymphopenia (an abnormally low level of lymphocytes in the blood): 25 people, 39.06%
  4. Blood Creatinine Increased: 10 people, 15.62%
  5. Gas Gangrene (bacterial infection that produces gas within tissues): 5 people, 7.81%
  6. Hypotension (abnormally low blood pressure): 5 people, 7.81%
  7. Blood Glucose Fluctuation: 5 people, 7.81%
  8. Acute Respiratory Failure: 5 people, 7.81%
  9. Septic Shock (shock due to blood infection): 5 people, 7.81%
  10. Metabolic Acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body): 5 people, 7.81%

What are the existing conditions these people have? *

  1. Anaesthesia: 7 people, 10.94%
  2. Spondylosis (a defect of a vertebra): 2 people, 3.12%
  3. Sleep Disorder: 2 people, 3.12%
  4. Procedural Pain: 2 people, 3.12%
  5. Pain: 2 people, 3.12%
  6. Nausea And Vomiting: 2 people, 3.12%
  7. Spinal Osteoarthritis (joint cartilage loss in spine): 1 person, 1.56%
  8. Essential Hypertension (primary hypertension): 1 person, 1.56%

* Approximation only. Some reports may have incomplete information.

Do you take Naropin and have Acute kidney failure?

- Check whether Acute kidney failure is associated with a drug or a condition
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Naropin:

Acute kidney failure treatments and more:

How severe was Acute kidney failure and when was it recovered:

Expand to all the drugs that have ingredients of ropivacaine hydrochloride monohydrate:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Naropin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Acute kidney failure:

Browse all the conditions that are associated with Acute kidney failure:


How the study uses the data?

The study uses data from the FDA. It is based on ropivacaine hydrochloride monohydrate (the active ingredients of Naropin) and Naropin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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