Neupogen and Bone swelling - a phase IV clinical study of FDA data

Summary:

Bone swelling is reported as a side effect among people who take Neupogen (filgrastim), especially for people who are female, 60+ old, have been taking the drug for 2 - 5 years also take Zometa, and have Multiple myeloma.

The phase IV clinical study analyzes which people have Bone swelling when taking Neupogen. It is created by eHealthMe based on reports of 23,793 people who have side effects when taking Neupogen from the FDA, and is updated regularly.

What is Neupogen?

Neupogen has active ingredients of filgrastim. It is often used in agranulocytosis. eHealthMe is studying from 23,898 Neupogen users. Check the latest studies of Neupogen.

What is Bone swelling?

Bone swelling is found to be associated with 374 drugs and 262 conditions by eHealthMe. Check the latest studies of Bone swelling.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 31, 2026

23,793 people reported to have side effects when taking Neupogen.
Among them, 51 people (0.21%) have Bone swelling.

Among these 51 people:

How long have people been on Neupogen when they have Bone swelling? *

What is the gender of people who have Bone swelling when taking Neupogen? *

female: 55.32 %
male: 44.68 %

What is the age of people who have Bone swelling when taking Neupogen? *

What are other drugs people take besides Neupogen? *

Zometa: 44 people, 86.27%
Aredia: 30 people, 58.82%
Thalidomide: 29 people, 56.86%
Lasix: 22 people, 43.14%
Zofran: 19 people, 37.25%
Melphalan Hydrochloride: 19 people, 37.25%
Ativan: 18 people, 35.29%
Zantac: 18 people, 35.29%
Dexamethasone: 18 people, 35.29%
Fosamax: 17 people, 33.33%

What are other side effects people have besides Bone swelling? *

Bone Disorder: 39 people, 76.47%
Pain: 35 people, 68.63%
Osteonecrosis Of Jaw (death of bone of jaw): 32 people, 62.75%
Jaw Disorder (jaw disease): 29 people, 56.86%
Stress And Anxiety: 28 people, 54.90%
Neuropathy Peripheral (surface nerve damage): 27 people, 52.94%
Cellulitis (infection under the skin): 27 people, 52.94%
Pain In Jaw: 25 people, 49.02%
Weight Decreased: 25 people, 49.02%
Fever: 23 people, 45.10%

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 31 people, 60.78%
Immunodeficiency Disorders: 16 people, 31.37%
Aseptic Necrosis (the death of bone tissue due to a lack of blood supply): 16 people, 31.37%
Pain: 14 people, 27.45%
Metastases To Bone (cancer spreads to bone): 8 people, 15.69%
Nausea (feeling of having an urge to vomit): 7 people, 13.73%
Breast Cancer: 6 people, 11.76%
Endometrial Cancer: 6 people, 11.76%
Ovarian Cancer (cancer of ovary): 6 people, 11.76%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 6 people, 11.76%

* Approximation only. Some reports may have incomplete information.

Do you take Neupogen and have Bone swelling?

- Check whether Bone swelling is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Neupogen:

Neupogen (23,898 reports)

Bone swelling treatments and more:

Bone swelling (1,519 reports)

Browse all side effects of Neupogen:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Bone swelling:

Bone swelling (374 drugs)

Browse all the conditions that are associated with Bone swelling:

Bone swelling (262 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on filgrastim (the active ingredients of Neupogen) and Neupogen (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.