Nexium and Bladder spasm - a phase IV clinical study of FDA data
Summary:
Bladder spasm is reported as a side effect among people who take Nexium (esomeprazole magnesium), especially for people who are female, 60+ old, have been taking the drug for 5 - 10 years also take Zantac, and have High blood cholesterol.
The phase IV clinical study analyzes which people have Bladder spasm when taking Nexium. It is created by eHealthMe based on reports of 240,870 people who have side effects when taking Nexium from the FDA, and is updated regularly.
What is Nexium?
Nexium has active ingredients of esomeprazole magnesium. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 245,677 Nexium users. Check the latest studies of Nexium.
What is Bladder spasm?
Bladder spasm is found to be associated with 341 drugs and 468 conditions by eHealthMe. Check the latest studies of Bladder spasm.
240,870 people reported to have side effects when taking Nexium.
Among them, 75 people (0.03%) have Bladder spasm.

Among these 75 people:
How long have people been on Nexium when they have Bladder spasm? *
- < 1 month: 0.0 %
- 1 - 6 months: 0.0 %
- 6 - 12 months: 0.0 %
- 1 - 2 years: 50 %
- 2 - 5 years: 0.0 %
- 5 - 10 years: 50 %
- 10+ years: 0.0 %
What is the gender of people who have Bladder spasm when taking Nexium? *
- female: 79.73 %
- male: 20.27 %
What is the age of people who have Bladder spasm when taking Nexium? *
- 0-1: 0.0 %
- 2-9: 0.0 %
- 10-19: 0.0 %
- 20-29: 0.0 %
- 30-39: 4.92 %
- 40-49: 9.84 %
- 50-59: 31.15 %
- 60+: 54.1 %
What are other drugs people take besides Nexium? *
- Zantac: 23 people, 30.67%
- Lyrica: 21 people, 28.00%
- Celebrex: 20 people, 26.67%
- Ambien: 20 people, 26.67%
- Percocet: 18 people, 24.00%
- Neurontin: 18 people, 24.00%
- Zometa: 17 people, 22.67%
- Aredia: 17 people, 22.67%
- Vioxx: 17 people, 22.67%
- Lidoderm: 16 people, 21.33%
What are other side effects people have besides Bladder spasm? *
- Pain In Extremity: 24 people, 32.00%
- Weakness: 22 people, 29.33%
- Pain: 22 people, 29.33%
- Urinary Tract Infection: 21 people, 28.00%
- Hypoaesthesia (reduced sense of touch or sensation): 20 people, 26.67%
- Stress And Anxiety: 20 people, 26.67%
- Osteopenia (a condition where bone mineral density is lower than normal): 20 people, 26.67%
- Neuropathy Peripheral (surface nerve damage): 18 people, 24.00%
- Fall: 18 people, 24.00%
- Emotional Distress: 17 people, 22.67%
What are the existing conditions these people have? *
- High Blood Cholesterol: 12 people, 16.00%
- Pain: 10 people, 13.33%
- Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 9 people, 12.00%
- Migraine (headache): 7 people, 9.33%
- Asthma: 7 people, 9.33%
- High Blood Pressure: 6 people, 8.00%
- Muscle Spasms (muscle contraction): 5 people, 6.67%
- Type 2 Diabetes: 4 people, 5.33%
- Multiple Myeloma (cancer of the plasma cells): 4 people, 5.33%
- Bone Disorder: 3 people, 4.00%
* Approximation only. Some reports may have incomplete information.
Do you take Nexium and have Bladder spasm?
- Check whether Bladder spasm is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, long term effects of, and alternative drugs to Nexium:
- Nexium (245,677 reports)
Bladder spasm treatments and more:
- Bladder spasm (3,924 reports)
How severe was Bladder spasm and when was it recovered:
Expand to all the drugs that have ingredients of esomeprazole magnesium:
Sub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Nexium:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all the drugs that are associated with Bladder spasm:
- Bladder spasm (341 drugs)
Browse all the conditions that are associated with Bladder spasm:
- Bladder spasm (468 conditions)
Related publications that referenced our studies
- Dr. Anthony Wong, "Esomeprazole and gynaecomastia in obese adults", WHO pharmaceuticals newsletter: 2019, No. 2, 2019 Jan .
- Dr. Anthony Wong, "Esomeprazole and gynaecomastia in obese adults", WHO pharmaceuticals newsletter: 2019, No. 2, 2019 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on esomeprazole magnesium (the active ingredients of Nexium) and Nexium (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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