Nexium and Haematotoxicity - a phase IV clinical study of FDA data
Summary:
Haematotoxicity is reported as a side effect among people who take Nexium (esomeprazole magnesium), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Lasix, and have Gastric cancer.
The phase IV clinical study analyzes which people have Haematotoxicity when taking Nexium. It is created by eHealthMe based on reports of 240,870 people who have side effects when taking Nexium from the FDA, and is updated regularly.
What is Nexium?
Nexium has active ingredients of esomeprazole magnesium. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 245,678 Nexium users. Check the latest studies of Nexium.
What is Haematotoxicity?
Haematotoxicity (toxins that destroy red blood cells) is found to be associated with 343 drugs and 830 conditions by eHealthMe. Check the latest studies of Haematotoxicity.
eHealthMe: drug outcomes in the real world
eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.
240,870 people reported to have side effects when taking Nexium.
Among them, 14 people (0.01%) have Haematotoxicity.

Among these 14 people:
How long have people been on Nexium when they have Haematotoxicity? *
- < 1 month: 50 %
- 1 - 6 months: 50 %
- 6 - 12 months: 0.0 %
- 1 - 2 years: 0.0 %
- 2 - 5 years: 0.0 %
- 5 - 10 years: 0.0 %
- 10+ years: 0.0 %
What is the gender of people who have Haematotoxicity when taking Nexium? *
- female: 66.67 %
- male: 33.33 %
What is the age of people who have Haematotoxicity when taking Nexium? *
- 0-1: 0.0 %
- 2-9: 0.0 %
- 10-19: 0.0 %
- 20-29: 0.0 %
- 30-39: 12.5 %
- 40-49: 12.5 %
- 50-59: 12.5 %
- 60+: 62.5 %
What are other drugs people take besides Nexium? *
- Amlodipine: 3 people, 21.43%
- Vitamin C: 3 people, 21.43%
- Diovan: 3 people, 21.43%
- Lasix: 3 people, 21.43%
- Calcium: 2 people, 14.29%
- Lipitor: 2 people, 14.29%
- Lovenox: 2 people, 14.29%
- Xgeva: 1 person, 7.14%
- Coq10: 1 person, 7.14%
- Gaviscon: 1 person, 7.14%
What are other side effects people have besides Haematotoxicity? *
- Liver Disorder (liver diseases): 4 people, 28.57%
- Gastric Cancer Stage Iv (cancer cells have spread to distant organs): 3 people, 21.43%
- Nausea (feeling of having an urge to vomit): 3 people, 21.43%
- Hypotension (abnormally low blood pressure): 3 people, 21.43%
- Overdose: 2 people, 14.29%
- Joint Pain: 2 people, 14.29%
- Hyperchlorhydria (gastric acid levels are higher in stomach): 2 people, 14.29%
- Hiatal Hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm): 2 people, 14.29%
- Weight Decreased: 2 people, 14.29%
- Glaucoma (increased fluid pressure in the eye with vision loss): 2 people, 14.29%
What are the existing conditions these people have? *
- Constipation: 4 people, 28.57%
- Gastric Cancer (stomach cancer): 4 people, 28.57%
- High Blood Pressure: 3 people, 21.43%
- Oesophagitis Ulcerative (inflammation of oesophagus with multiple ulcers): 3 people, 21.43%
- Oedema Due To Hepatic Disease (fluid collection in tissue due to liver disease): 3 people, 21.43%
- Gastritis (inflammation of stomach): 3 people, 21.43%
- Glaucoma (increased fluid pressure in the eye with vision loss): 2 people, 14.29%
- Central Nervous System Lymphoma (cancer of central nervous system forms in lymph tissue): 2 people, 14.29%
- Hiatal Hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm): 2 people, 14.29%
- Hernia (hernia happens when part of an internal organ or tissue bulges through a weak area of muscle): 2 people, 14.29%
* Approximation only. Some reports may have incomplete information.
Do you take Nexium and have Haematotoxicity?
- Check whether Haematotoxicity is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, long term effects of, and alternative drugs to Nexium:
- Nexium (245,678 reports)
Haematotoxicity treatments and more:
- Haematotoxicity (8,984 reports)
How severe was Haematotoxicity and when was it recovered:
Expand to all the drugs that have ingredients of esomeprazole magnesium:
Sub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Nexium:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all the drugs that are associated with Haematotoxicity:
- Haematotoxicity (343 drugs)
Browse all the conditions that are associated with Haematotoxicity:
- Haematotoxicity (830 conditions)
Related publications that referenced our studies
- Dr. Anthony Wong, "Esomeprazole and gynaecomastia in obese adults", WHO pharmaceuticals newsletter: 2019, No. 2, 2019 Jan .
- Dr. Anthony Wong, "Esomeprazole and gynaecomastia in obese adults", WHO pharmaceuticals newsletter: 2019, No. 2, 2019 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on esomeprazole magnesium (the active ingredients of Nexium) and Nexium (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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