Nubain and Weakness - a phase IV clinical study of FDA data

Summary:

Weakness is reported as a side effect among people who take Nubain (nalbuphine hydrochloride), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Zofran, and have Idiopathic thrombocytopenic purpura.

The phase IV clinical study analyzes which people have Weakness when taking Nubain. It is created by eHealthMe based on reports of 1,718 people who have side effects when taking Nubain from the FDA, and is updated regularly.

What is Nubain?

Nubain has active ingredients of nalbuphine hydrochloride. It is often used in pain. eHealthMe is studying from 1,749 Nubain users. Check the latest studies of Nubain.

What is Weakness?

Weakness is found to be associated with 3,640 drugs and 6,613 conditions by eHealthMe. Check the latest studies of Weakness.



On Jul, 29, 2026

1,718 people reported to have side effects when taking Nubain.
Among them, 40 people (2.33%) have Weakness.

Could Nubain cause Weakness?

Among these 40 people:

How long have people been on Nubain when they have Weakness? *

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Weakness when taking Nubain? *

  • female: 65.79 %
  • male: 34.21 %

What is the age of people who have Weakness when taking Nubain? *

  • 0-1: 0.0 %
  • 2-9: 2.86 %
  • 10-19: 5.71 %
  • 20-29: 14.29 %
  • 30-39: 17.14 %
  • 40-49: 8.57 %
  • 50-59: 20.0 %
  • 60+: 31.43 %

What are other drugs people take besides Nubain? *

  1. Zofran: 10 people, 25.00%
  2. Ibuprofen: 8 people, 20.00%
  3. Levaquin: 8 people, 20.00%
  4. Pepcid: 7 people, 17.50%
  5. Ambien: 7 people, 17.50%
  6. Toradol: 7 people, 17.50%
  7. Tylenol: 7 people, 17.50%
  8. Ultram: 7 people, 17.50%
  9. Soma: 7 people, 17.50%
  10. Fish Oil: 6 people, 15.00%

What are other side effects people have besides Weakness? *

  1. Nausea (feeling of having an urge to vomit): 17 people, 42.50%
  2. Chest Pain: 13 people, 32.50%
  3. Fatigue (feeling of tiredness): 12 people, 30.00%
  4. Headache (pain in head): 12 people, 30.00%
  5. Pain In Extremity: 11 people, 27.50%
  6. Muscle Aches (muscle pain): 10 people, 25.00%
  7. Nausea And Vomiting: 9 people, 22.50%
  8. Gait Disturbance: 8 people, 20.00%
  9. Head Injury: 8 people, 20.00%
  10. Dyspnea (difficult or laboured breathing): 8 people, 20.00%

What are the existing conditions these people have? *

  1. Idiopathic Thrombocytopenic Purpura (bleeding disorder in which the immune system destroys platelets, which are necessary for normal blood clotting): 3 people, 7.50%
  2. Weight Loss: 2 people, 5.00%
  3. Cystitis Interstitial (unknown cause characterized by bladder pain): 2 people, 5.00%
  4. Headache (pain in head): 2 people, 5.00%
  5. High Blood Pressure: 1 person, 2.50%
  6. Arthritis (form of joint disorder that involves inflammation of one or more joints): 1 person, 2.50%
  7. Asthma: 1 person, 2.50%
  8. Birth Control: 1 person, 2.50%
  9. Breast Cancer: 1 person, 2.50%
  10. Cardiomyopathy (weakening of the heart muscle): 1 person, 2.50%

* Approximation only. Some reports may have incomplete information.

Do you take Nubain and have Weakness?

- Check whether Weakness is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Nubain:

Weakness treatments and more:

How severe was Weakness and when was it recovered:

Expand to all the drugs that have ingredients of nalbuphine hydrochloride:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Nubain:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Weakness:

Browse all the conditions that are associated with Weakness:


How the study uses the data?

The study uses data from the FDA. It is based on nalbuphine hydrochloride (the active ingredients of Nubain) and Nubain (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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