Nucynta and Confusion - a phase IV clinical study of FDA data

Summary:

Confusion is reported as a side effect among people who take Nucynta (tapentadol hydrochloride), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Valium, and have Procedural pain.

The phase IV clinical study analyzes which people have Confusion when taking Nucynta. It is created by eHealthMe based on reports of 31,342 people who have side effects when taking Nucynta from the FDA, and is updated regularly.

What is Nucynta?

Nucynta has active ingredients of tapentadol hydrochloride. It is often used in pain. eHealthMe is studying from 31,818 Nucynta users. Check the latest studies of Nucynta.

What is Confusion?

Confusion is found to be associated with 1,832 drugs and 2,825 conditions by eHealthMe. Check the latest studies of Confusion.



On Jul, 13, 2026

31,342 people reported to have side effects when taking Nucynta.
Among them, 59 people (0.19%) have Confusion.

Could Nucynta cause Confusion?

Among these 59 people:

How long have people been on Nucynta when they have Confusion? *

  • < 1 month: 81.25 %
  • 1 - 6 months: 18.75 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Confusion when taking Nucynta? *

  • female: 48.94 %
  • male: 51.06 %

What is the age of people who have Confusion when taking Nucynta? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 5.71 %
  • 40-49: 20.0 %
  • 50-59: 25.71 %
  • 60+: 48.57 %

What are other drugs people take besides Nucynta? *

  1. Melatonin: 4 people, 6.78%
  2. Singulair: 4 people, 6.78%
  3. Januvia: 4 people, 6.78%
  4. Percocet: 4 people, 6.78%
  5. Dexilant: 4 people, 6.78%
  6. Claritin: 4 people, 6.78%
  7. Simvastatin: 4 people, 6.78%
  8. Lisinopril: 4 people, 6.78%
  9. Valium: 4 people, 6.78%
  10. Crestor: 3 people, 5.08%

What are other side effects people have besides Confusion? *

  1. Confusional State: 24 people, 40.68%
  2. Dizziness: 13 people, 22.03%
  3. Hallucinations (sensations that appear real but are created by your mind): 11 people, 18.64%
  4. Speech Impairment (Adult) (inability to speak (adult)): 10 people, 16.95%
  5. Headache (pain in head): 8 people, 13.56%
  6. Abnormal Behavior: 8 people, 13.56%
  7. Nausea (feeling of having an urge to vomit): 8 people, 13.56%
  8. Hallucination, Visual (seeing things that aren't there): 7 people, 11.86%
  9. Aggression: 7 people, 11.86%
  10. Drowsiness: 7 people, 11.86%

What are the existing conditions these people have? *

  1. Diabetes: 6 people, 10.17%
  2. Procedural Pain: 6 people, 10.17%
  3. Sleep Disorder: 5 people, 8.47%
  4. Fibromyalgia (a long-term condition which causes pain all over the body): 4 people, 6.78%
  5. Multiple Allergies (allergy to multiple agents): 4 people, 6.78%
  6. Migraine (headache): 3 people, 5.08%
  7. Neuralgia (pain in one or more nerves): 3 people, 5.08%
  8. Neck Pain: 3 people, 5.08%
  9. Stress And Anxiety: 2 people, 3.39%
  10. Musculoskeletal Pain (pain affects the bones, muscles, ligaments, tendons, and nerves): 2 people, 3.39%

* Approximation only. Some reports may have incomplete information.

Do you take Nucynta and have Confusion?

- Check whether Confusion is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Nucynta:

Confusion treatments and more:

How severe was Confusion and when was it recovered:

Expand to all the drugs that have ingredients of tapentadol hydrochloride:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Nucynta:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Confusion:

Browse all the conditions that are associated with Confusion:


How the study uses the data?

The study uses data from the FDA. It is based on tapentadol hydrochloride (the active ingredients of Nucynta) and Nucynta (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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