Zyrtec and Claravis drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Zyrtec (cetirizine hydrochloride) and Claravis (isotretinoin). Common drug interactions include colitis ulcerative among females and depression among males.

The phase IV clinical study analyzes what interactions people have when they take Zyrtec and Claravis. It is created by eHealthMe based on reports of 57 people who take the same drugs from the FDA, and is updated regularly.

What is Zyrtec?

Zyrtec has active ingredients of cetirizine hydrochloride. It is often used in allergies. eHealthMe is studying from 114,619 Zyrtec users. Check the latest studies of Zyrtec.

What is Claravis?

Claravis has active ingredients of isotretinoin. It is often used in acne. eHealthMe is studying from 9,636 Claravis users. Check the latest studies of Claravis.

On Jul, 13, 2026

57 people who take Zyrtec and Claravis together, and have interactions are studied.

What are the common drug interactions of Zyrtec and Claravis, by gender? *:

female:

Colitis ulcerative (inflammation of colon with ulcer)
Cytomegalovirus test positive
Diarrhoea
Dry skin
Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters)
Foot fracture
Gastritis (inflammation of stomach)
Gastrointestinal disorder (functional problems of gastrointestinal tract)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Headache (pain in head)

male:

Depression
Inflammatory bowel disease
Dry skin
Epistaxis (bleed from the nose)
Erythema (redness of the skin)
Intestinal obstruction
Irritable bowel syndrome
Myalgia (muscle pain)
Nasal dryness (dry nose)
Nasopharyngitis (inflammation of the nasopharynx)

What are the common drug interactions of Zyrtec and Claravis, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Depression
Mood altered (changes in mood)
Anal fissure
Colitis (inflammation of colon)
Crohn's disease (a condition that causes inflammation of the gastrointestinal tract)
Dry eye (lack of adequate tears)
Infected cyst
Inflammatory bowel disease
Iron deficiency anaemia
Oral herpes (viral infection of mouth)

20-29:

Stress
Suicidal ideation
Anxiety
Attention deficit hyperactivity disorder (a chronic condition including attention difficulty, hyperactivity, and impulsiveness)
Binge drinking (excessive alcohol use)
Binge eating (pattern of disordered eating which consists of episodes of uncontrollable eating)
Bipolar disorder (mood disorder)
Depression
Fatigue (feeling of tiredness)
Hallucination (an experience involving the perception of something not present)

30-39:

Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters)

40-49:

Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Pulmonary embolism (blockage of the main artery of the lung)
Unintended pregnancy (unwanted pregnancies as well as those that are mistimed)

50-59:

Abdominal pain
Intestinal obstruction
Irritable bowel syndrome
Lip dry
Myalgia (muscle pain)
Nasal dryness (dry nose)
Nasopharyngitis (inflammation of the nasopharynx)
Nausea (feeling of having an urge to vomit)
Rash
Rectal haemorrhage (bleeding from anus)

60+:

Drug hypersensitivity

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 11 people, 19.30%
Drowsiness: 5 people, 8.77%
Acne Cystic (skin problems that cause pimples): 5 people, 8.77%
Stress And Anxiety: 3 people, 5.26%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 3 people, 5.26%

* Approximation only. Some reports may have incomplete information.

Do you take Zyrtec and Claravis?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously