Nucynta and Nosebleed - a phase IV clinical study of FDA data

Summary:

Nosebleed is reported as a side effect among people who take Nucynta (tapentadol hydrochloride), especially for people who are female, 50-59 old, also take Potassium Chloride, and have Polymyositis.

The phase IV clinical study analyzes which people have Nosebleed when taking Nucynta. It is created by eHealthMe based on reports of 31,342 people who have side effects when taking Nucynta from the FDA, and is updated regularly.

What is Nucynta?

Nucynta has active ingredients of tapentadol hydrochloride. It is often used in pain. eHealthMe is studying from 31,818 Nucynta users. Check the latest studies of Nucynta.

What is Nosebleed?

Nosebleed (bleeding from nose) is found to be associated with 2,080 drugs and 3,092 conditions by eHealthMe. Check the latest studies of Nosebleed.

On Jul, 14, 2026

31,342 people reported to have side effects when taking Nucynta.
Among them, 14 people (0.04%) have Nosebleed.

Among these 14 people:

What is the gender of people who have Nosebleed when taking Nucynta? *

female: 91.67 %
male: 8.33 %

What is the age of people who have Nosebleed when taking Nucynta? *

What are other drugs people take besides Nucynta? *

Potassium: 4 people, 28.57%
Ondansetron: 4 people, 28.57%
Singulair: 4 people, 28.57%
Heparin: 4 people, 28.57%
Synthroid: 4 people, 28.57%
Potassium Chloride: 4 people, 28.57%
Diphenhydramine Hydrochloride: 3 people, 21.43%
Percocet: 3 people, 21.43%
Klor-Con: 3 people, 21.43%
Hydrocodone Bitartrate And Acetaminophen: 3 people, 21.43%

What are other side effects people have besides Nosebleed? *

Joint Pain: 4 people, 28.57%
Peripheral Swelling: 4 people, 28.57%
Nausea (feeling of having an urge to vomit): 4 people, 28.57%
Haemorrhage (bleeding): 4 people, 28.57%
Headache (pain in head): 4 people, 28.57%
Scab (a hard coating on the skin formed during the wound healing): 4 people, 28.57%
Joint Injury: 3 people, 21.43%
Nausea And Vomiting: 3 people, 21.43%
Nasal Congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels): 3 people, 21.43%
Muscle Twitching: 3 people, 21.43%

What are the existing conditions these people have? *

Pulmonary Hypertension (increase in blood pressure in the lung artery): 3 people, 21.43%
Polymyositis (inflammatory muscle disease that causes weakness of the skeletal muscles): 3 people, 21.43%
Thrombosis (formation of a blood clot inside a blood vessel): 1 person, 7.14%
Renal Disorder (kidney disease): 1 person, 7.14%
Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 1 person, 7.14%
Raynaud's Phenomenon (discoloration of the fingers, toes, and occasionally other areas): 1 person, 7.14%
Post Procedural Pain: 1 person, 7.14%
Inflammation: 1 person, 7.14%
Hepatitis C: 1 person, 7.14%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

Do you take Nucynta and have Nosebleed?

- Check whether Nosebleed is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Nucynta:

Nucynta (31,818 reports)

Nosebleed treatments and more:

Nosebleed (92,075 reports)

Browse all side effects of Nucynta:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Nosebleed:

Nosebleed (2,080 drugs)

Browse all the conditions that are associated with Nosebleed:

Nosebleed (3,092 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on tapentadol hydrochloride (the active ingredients of Nucynta) and Nucynta (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.