Onfi and Acute kidney failure - a phase IV clinical study of FDA data

Summary:

Acute kidney failure is reported as a side effect among people who take Onfi (clobazam), especially for people who are male, 10-19 old, have been taking the drug for < 1 month also take Keppra, and have Complex partial seizures.

The phase IV clinical study analyzes which people have Acute kidney failure when taking Onfi. It is created by eHealthMe based on reports of 7,698 people who have side effects when taking Onfi from the FDA, and is updated regularly.

What is Onfi?

Onfi has active ingredients of clobazam. It is often used in epilepsy. eHealthMe is studying from 7,809 Onfi users. Check the latest studies of Onfi.

What is Acute kidney failure?

Acute kidney failure is found to be associated with 2,836 drugs and 4,493 conditions by eHealthMe. Check the latest studies of Acute kidney failure.

On Jul, 27, 2026

7,698 people reported to have side effects when taking Onfi.
Among them, 12 people (0.16%) have Acute kidney failure.

Among these 12 people:

How long have people been on Onfi when they have Acute kidney failure? *

What is the gender of people who have Acute kidney failure when taking Onfi? *

female: 41.67 %
male: 58.33 %

What is the age of people who have Acute kidney failure when taking Onfi? *

What are other drugs people take besides Onfi? *

What are other side effects people have besides Acute kidney failure? *

Fever: 2 people, 16.67%
Status Epilepticus (a life-threatening condition in which the brain is in a state of persistent seizure): 2 people, 16.67%
Cholangitis (infection of the bile duct): 2 people, 16.67%
Cholestasis (a condition where bile cannot flow from the liver to the duodenum): 2 people, 16.67%
Pneumonia: 2 people, 16.67%
Volvulus (obstruction caused by twisting of the stomach or intestine): 1 person, 8.33%
Dehydration (dryness resulting from the removal of water): 1 person, 8.33%
Haematuria (presence of blood in urine): 1 person, 8.33%
Gastrointestinal Necrosis (destruction of gastrointestinal organ): 1 person, 8.33%
Foetal Heart Rate Disorder: 1 person, 8.33%

What are the existing conditions these people have? *

Complex Partial Seizures (epileptic seizure): 2 people, 16.67%
Stress And Anxiety: 1 person, 8.33%
Renal Impairment (severely reduced kidney function): 1 person, 8.33%
Pain: 1 person, 8.33%
Muscle Spasms (muscle contraction): 1 person, 8.33%
Infantile Spasms: 1 person, 8.33%
High Blood Pressure: 1 person, 8.33%
Gastrointestinal Disorder (functional problems of gastrointestinal tract): 1 person, 8.33%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 8.33%
Angiomyolipoma (most common benign tumour of the kidney): 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Onfi and have Acute kidney failure?

- Check whether Acute kidney failure is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Onfi:

Onfi (7,809 reports)

Browse all side effects of Onfi:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Acute kidney failure:

Acute kidney failure (2,836 drugs)

Browse all the conditions that are associated with Acute kidney failure:

Acute kidney failure (4,493 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on clobazam (the active ingredients of Onfi) and Onfi (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.