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Oxbryta and Heart rate increased - a phase IV clinical study of FDA data

Summary:

Heart rate increased is reported as a side effect among people who take Oxbryta (voxelotor), especially for people who are female, 50-59 old, have been taking the drug for < 1 month also take Hydroxyurea, and have Haemochromatosis.

The phase IV clinical study analyzes which people have Heart rate increased when taking Oxbryta. It is created by eHealthMe based on reports of 24,969 people who have side effects when taking Oxbryta from the FDA, and is updated regularly.

What is Oxbryta?

Oxbryta has active ingredients of voxelotor. eHealthMe is studying from 24,969 Oxbryta users. Check the latest studies of Oxbryta.

What is Heart rate increased?

Heart rate increased is found to be associated with 2,387 drugs and 3,212 conditions by eHealthMe. Check the latest studies of Heart rate increased.

On Jul, 09, 2026

24,969 people reported to have side effects when taking Oxbryta.
Among them, 35 people (0.14%) have Heart rate increased.

Could Oxbryta cause Heart rate increased?

Among these 35 people:

How long have people been on Oxbryta when they have Heart rate increased? *

  • < 1 month: 66.67 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 22.22 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 11.11 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Heart rate increased when taking Oxbryta? *

  • female: 88.57 %
  • male: 11.43 %

What is the age of people who have Heart rate increased when taking Oxbryta? *

  • 0-1: 0.0 %
  • 2-9: 8 %
  • 10-19: 4 %
  • 20-29: 12 %
  • 30-39: 4 %
  • 40-49: 12 %
  • 50-59: 36 %
  • 60+: 24 %

What are other drugs people take besides Oxbryta? *

  1. Hydroxyurea: 3 people, 8.57%
  2. Lasix: 2 people, 5.71%
  3. Tacrolimus: 2 people, 5.71%
  4. Nifedipine: 2 people, 5.71%
  5. Amlodipine: 2 people, 5.71%
  6. Remodulin: 1 person, 2.86%
  7. Orenitram: 1 person, 2.86%
  8. Tylenol: 1 person, 2.86%
  9. Motrin: 1 person, 2.86%
  10. Morphine: 1 person, 2.86%

What are other side effects people have besides Heart rate increased? *

  1. Diarrhea: 13 people, 37.14%
  2. Fatigue (feeling of tiredness): 11 people, 31.43%
  3. Haemoglobin Decreased: 9 people, 25.71%
  4. Headache (pain in head): 8 people, 22.86%
  5. Itching: 7 people, 20.00%
  6. Chest Pain: 7 people, 20.00%
  7. Nausea (feeling of having an urge to vomit): 7 people, 20.00%
  8. Abdominal Pain Upper: 6 people, 17.14%
  9. Fever: 5 people, 14.29%
  10. Peripheral Swelling: 5 people, 14.29%

What are the existing conditions these people have? *

  1. Thrombosis (formation of a blood clot inside a blood vessel): 1 person, 2.86%
  2. Pulmonary Embolism (blockage of the main artery of the lung): 1 person, 2.86%
  3. Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 1 person, 2.86%
  4. Pain: 1 person, 2.86%
  5. Haemochromatosis (body to absorb more iron than usual from food): 1 person, 2.86%

* Approximation only. Some reports may have incomplete information.

Do you take Oxbryta and have Heart rate increased?

- Check whether Heart rate increased is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Oxbryta:

Heart rate increased treatments and more:

How severe was Heart rate increased and when was it recovered:

Expand to all the drugs that have ingredients of voxelotor:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Oxbryta:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Heart rate increased:

Browse all the conditions that are associated with Heart rate increased:

How the study uses the data?

The study uses data from the FDA. It is based on voxelotor (the active ingredients of Oxbryta) and Oxbryta (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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