Oxycodone and Calciphylaxis - a phase IV clinical study of FDA data

Summary:

Calciphylaxis is reported as a side effect among people who take Oxycodone (oxycodone hydrochloride), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Ramipril, and have Cytomegalovirus viraemia.

The phase IV clinical study analyzes which people have Calciphylaxis when taking Oxycodone. It is created by eHealthMe based on reports of 159,853 people who have side effects when taking Oxycodone from the FDA, and is updated regularly.

What is Oxycodone?

Oxycodone has active ingredients of oxycodone hydrochloride. It is often used in pain. eHealthMe is studying from 162,588 Oxycodone users. Check the latest studies of Oxycodone.

What is Calciphylaxis?

Calciphylaxis (is a syndrome with vascular calcium accumulation) is found to be associated with 139 drugs and 382 conditions by eHealthMe. Check the latest studies of Calciphylaxis.



On Jan, 29, 2026

159,853 people reported to have side effects when taking Oxycodone.
Among them, 17 people (0.01%) have Calciphylaxis.

Could Oxycodone cause Calciphylaxis?

Among these 17 people:

How long have people been on Oxycodone when they have Calciphylaxis? *

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Calciphylaxis when taking Oxycodone? *

  • female: 94.12 %
  • male: 5.88 %

What is the age of people who have Calciphylaxis when taking Oxycodone? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 6.25 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 12.5 %
  • 60+: 81.25 %

What are other drugs people take besides Oxycodone? *

  1. Acetaminophen: 5 people, 29.41%
  2. Gabapentin: 5 people, 29.41%
  3. Sodium Thiosulfate: 5 people, 29.41%
  4. Prednisone: 5 people, 29.41%
  5. Ramipril: 5 people, 29.41%
  6. Letermovir: 4 people, 23.53%
  7. Mycophenolic Acid: 4 people, 23.53%
  8. Tacrolimus: 4 people, 23.53%
  9. Calcium: 3 people, 17.65%
  10. Ganciclovir: 3 people, 17.65%

What are other side effects people have besides Calciphylaxis? *

  1. Skin Ulcer: 5 people, 29.41%
  2. Wound Infection: 4 people, 23.53%
  3. Pseudomonal Bacteraemia (p. aeruginosa cause of bacterial infections of the blood): 3 people, 17.65%
  4. International Normalised Ratio Increased: 3 people, 17.65%
  5. Inflammation: 3 people, 17.65%
  6. Neurotoxicity (when the exposure to natural or artificial toxic substances, which are called neurotoxins, alters the normal activity of the nervous system): 3 people, 17.65%
  7. Drug Ineffective: 3 people, 17.65%
  8. Diabetic Ulcer: 3 people, 17.65%
  9. Pulmonary Nocardiosis (lung infection by inhalation of nocardia spores): 3 people, 17.65%
  10. Rectal Haemorrhage (bleeding from anus): 3 people, 17.65%

What are the existing conditions these people have? *

  1. Cytomegalovirus Viraemia (cytomegalo virus in blood stream): 4 people, 23.53%
  2. High Blood Pressure: 3 people, 17.65%
  3. Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 2 people, 11.76%
  4. Hyperphosphataemia (electrolyte disturbance in which there is an abnormally elevated level of phosphate in the blood): 2 people, 11.76%
  5. Thyroid Cancer: 2 people, 11.76%
  6. Blood Magnesium Decreased: 1 person, 5.88%
  7. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 5.88%
  8. Herpes Zoster: 1 person, 5.88%
  9. Hypercalcaemia (elevated calcium (ca+) level in the blood): 1 person, 5.88%
  10. Hyperparathyroidism (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium): 1 person, 5.88%

* Approximation only. Some reports may have incomplete information.

Do you take Oxycodone and have Calciphylaxis?

- Check whether Calciphylaxis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Oxycodone:

Calciphylaxis treatments and more:

How severe was Calciphylaxis and when was it recovered:

Expand to all the drugs that have ingredients of oxycodone hydrochloride:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Oxycodone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Calciphylaxis:

Browse all the conditions that are associated with Calciphylaxis:

Drugs similar to Oxycodone and Calciphylaxis :


How the study uses the data?

The study uses data from the FDA. It is based on oxycodone hydrochloride (the active ingredients of Oxycodone) and Oxycodone (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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