Oxycodone and Reflux - a phase IV clinical study of FDA data

Summary:

Reflux is reported as a side effect among people who take Oxycodone (oxycodone hydrochloride), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Prilosec, and have High blood pressure.

The phase IV clinical study analyzes which people have Reflux when taking Oxycodone. It is created by eHealthMe based on reports of 159,853 people who have side effects when taking Oxycodone from the FDA, and is updated regularly.

What is Oxycodone?

Oxycodone has active ingredients of oxycodone hydrochloride. It is often used in pain. eHealthMe is studying from 162,588 Oxycodone users. Check the latest studies of Oxycodone.

What is Reflux?

Reflux (stomach contents come back up into the food pipe (gullet or oesophagus) or even into the mouth) is found to be associated with 2,576 drugs and 3,455 conditions by eHealthMe. Check the latest studies of Reflux.

On Jan, 08, 2026

159,853 people reported to have side effects when taking Oxycodone.
Among them, 1,672 people (1.05%) have Reflux.

Among these 1,672 people:

* Approximation only. Some reports may have incomplete information.

Do you take Oxycodone and have Reflux?

- Check whether Reflux is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Oxycodone:

Oxycodone (162,588 reports)

Reflux treatments and more:

Reflux (445,777 reports)

How severe was Reflux and when was it recovered:

Reflux in Oxycodone

Expand to all the drugs that have ingredients of oxycodone hydrochloride:

Reflux and drugs with ingredients of oxycodone hydrochloride (2,822 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Common Oxycodone side effects:

Browse all side effects of Oxycodone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Common drugs associated with Reflux:

Browse all the drugs that are associated with Reflux:

Reflux (2,576 drugs)

Common conditions associated with Reflux:

Hypertension: 8,809 reports
Blood pressure increased: 8,796 reports
Gerd: 8,087 reports
Heartburn - chronic: 7,618 reports
Osteoporosis: 6,424 reports
Thin bones: 6,141 reports
Reflux esophagitis: 5,786 reports
Pain: 5,547 reports
Alternative medicine - pain relief: 5,525 reports
Non-cardiac chest pain: 5,263 reports

Browse all the conditions that are associated with Reflux:

Reflux (3,455 conditions)

Drugs similar to Oxycodone and Reflux :

How the study uses the data?

The study uses data from the FDA. It is based on oxycodone hydrochloride (the active ingredients of Oxycodone) and Oxycodone (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.