Morphine and Reflux - a phase IV clinical study of FDA data

Summary:

Reflux is reported as a side effect among people who take Morphine (morphine sulfate), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Zometa, and have Asthma.

The phase IV clinical study analyzes which people have Reflux when taking Morphine. It is created by eHealthMe based on reports of 180,723 people who have side effects when taking Morphine from the FDA, and is updated regularly.

What is Morphine?

Morphine has active ingredients of morphine sulfate. It is often used in pain. eHealthMe is studying from 182,913 Morphine users. Check the latest studies of Morphine.

What is Reflux?

Reflux (stomach contents come back up into the food pipe (gullet or oesophagus) or even into the mouth) is found to be associated with 2,584 drugs and 3,451 conditions by eHealthMe. Check the latest studies of Reflux.

On Oct, 15, 2025

180,723 people reported to have side effects when taking Morphine.
Among them, 1,893 people (1.05%) have Reflux.

Among these 1,893 people:

* Approximation only. Some reports may have incomplete information.

Do you take Morphine and have Reflux?

- Check whether Reflux is associated with a drug or a condition (FREE)
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Morphine:

Morphine (182,913 reports)

Reflux treatments and more:

Reflux (445,752 reports)

How severe was Reflux and when was it recovered:

Reflux in Morphine

Expand to all the drugs that have ingredients of morphine sulfate:

Reflux and drugs with ingredients of morphine sulfate (2,241 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Common Morphine side effects:

Browse all side effects of Morphine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Common drugs associated with Reflux:

Browse all the drugs that are associated with Reflux:

Reflux (2,584 drugs)

Common conditions associated with Reflux:

Hypertension: 8,809 reports
High blood pressure: 8,796 reports
Reflux: 8,087 reports
Heartburn - chronic: 7,618 reports
Osteoporosis: 6,424 reports
Thin bones: 6,141 reports
Reflux esophagitis: 5,786 reports
Pain exacerbated: 5,547 reports
Pain relief: 5,525 reports
Gastro-oesophageal reflux disease: 5,263 reports

Browse all the conditions that are associated with Reflux:

Reflux (3,451 conditions)

Drugs similar to Morphine and Reflux :

Related publications that referenced our studies

Rasmy A, Rahal M, Kisana M, Ahmad S, Salah A, "Morphine induced thrombocytopenia: A case report", Journal of Case Reports and Images in Oncology, 2015 Dec .
Rasmy A, Rahal M, Kisana M, Ahmad S, Salah A, "Morphine induced thrombocytopenia: A case report", Journal of Case Reports and Images in Oncology, 2015 Dec .

How the study uses the data?

The study uses data from the FDA. It is based on morphine sulfate (the active ingredients of Morphine) and Morphine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.