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Pacerone and Oedema - a phase IV clinical study of FDA data

Summary:

Oedema is reported as a side effect among people who take Pacerone (amiodarone hydrochloride), especially for people who are female, 60+ old, also take Cordarone, and have Primary pulmonary hypertension.

The phase IV clinical study analyzes which people have Oedema when taking Pacerone. It is created by eHealthMe based on reports of 2,705 people who have side effects when taking Pacerone from the FDA, and is updated regularly.

What is Pacerone?

Pacerone has active ingredients of amiodarone hydrochloride. It is often used in atrial fibrillation/flutter. eHealthMe is studying from 2,814 Pacerone users. Check the latest studies of Pacerone.

What is Oedema?

Oedema (fluid collection in tissue) is found to be associated with 2,193 drugs and 2,311 conditions by eHealthMe. Check the latest studies of Oedema.

On Jul, 20, 2026

2,705 people reported to have side effects when taking Pacerone.
Among them, 57 people (2.11%) have Oedema.

Could Pacerone cause Oedema?

Among these 57 people:

What is the gender of people who have Oedema when taking Pacerone? *

  • female: 66.67 %
  • male: 33.33 %

What is the age of people who have Oedema when taking Pacerone? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 13.79 %
  • 50-59: 20.69 %
  • 60+: 65.52 %

What are other drugs people take besides Pacerone? *

  1. Cordarone: 29 people, 50.88%
  2. Aspirin: 21 people, 36.84%
  3. Digoxin: 13 people, 22.81%
  4. Lipitor: 12 people, 21.05%
  5. Coreg: 12 people, 21.05%
  6. Plavix: 11 people, 19.30%
  7. Furosemide: 10 people, 17.54%
  8. Nitroglycerin: 10 people, 17.54%
  9. Synthroid: 10 people, 17.54%
  10. Simvastatin: 10 people, 17.54%

What are other side effects people have besides Oedema? *

  1. Dyspnea (difficult or laboured breathing): 33 people, 57.89%
  2. Weakness: 26 people, 45.61%
  3. Fatigue (feeling of tiredness): 26 people, 45.61%
  4. Cough: 24 people, 42.11%
  5. Chest Pain: 22 people, 38.60%
  6. Dizziness: 20 people, 35.09%
  7. Pneumonia: 19 people, 33.33%
  8. Cardiac Failure Congestive: 15 people, 26.32%
  9. Adverse Drug Reaction: 14 people, 24.56%
  10. Cellulitis (infection under the skin): 14 people, 24.56%

What are the existing conditions these people have? *

  1. Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 10 people, 17.54%
  2. Multiple Myeloma (cancer of the plasma cells): 8 people, 14.04%
  3. Oral Pain: 3 people, 5.26%
  4. Nausea (feeling of having an urge to vomit): 3 people, 5.26%
  5. Ventricular Dysfunction (heart dysfunction): 1 person, 1.75%
  6. Sinus Rhythm (normal beating of the heart): 1 person, 1.75%
  7. Pulmonary Hypertension (increase in blood pressure in the lung artery): 1 person, 1.75%
  8. Pain: 1 person, 1.75%
  9. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 1 person, 1.75%
  10. Monoclonal Gammopathy: 1 person, 1.75%

* Approximation only. Some reports may have incomplete information.

Do you take Pacerone and have Oedema?

- Check whether Oedema is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Pacerone:

Oedema treatments and more:

How severe was Oedema and when was it recovered:

Expand to all the drugs that have ingredients of amiodarone hydrochloride:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Pacerone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Oedema:

Browse all the conditions that are associated with Oedema:

Related publications that referenced our studies

How the study uses the data?

The study uses data from the FDA. It is based on amiodarone hydrochloride (the active ingredients of Pacerone) and Pacerone (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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