Paclitaxel and Restless leg syndrome - a phase IV clinical study of FDA data

Summary:

Restless leg syndrome is reported as a side effect among people who take Paclitaxel (paclitaxel), especially for people who are female, 60+ old, have been taking the drug for 1 - 6 months also take Neulasta, and have Endometrial cancer.

The phase IV clinical study analyzes which people have Restless leg syndrome when taking Paclitaxel. It is created by eHealthMe based on reports of 85,850 people who have side effects when taking Paclitaxel from the FDA, and is updated regularly.

What is Paclitaxel?

Paclitaxel has active ingredients of paclitaxel. It is often used in breast cancer. eHealthMe is studying from 85,928 Paclitaxel users. Check the latest studies of Paclitaxel.

What is Restless leg syndrome?

Restless leg syndrome (a powerful urge to move your legs) is found to be associated with 1,245 drugs and 1,933 conditions by eHealthMe. Check the latest studies of Restless leg syndrome.

On Jul, 04, 2026

85,850 people reported to have side effects when taking Paclitaxel.
Among them, 26 people (0.03%) have Restless leg syndrome.

Could Paclitaxel cause Restless leg syndrome?

Among these 26 people:

How long have people been on Paclitaxel when they have Restless leg syndrome? *

What is the gender of people who have Restless leg syndrome when taking Paclitaxel? *

female: 92.31 %
male: 7.69 %

What is the age of people who have Restless leg syndrome when taking Paclitaxel? *

What are other drugs people take besides Paclitaxel? *

What are other side effects people have besides Restless leg syndrome? *

Insomnia (sleeplessness): 8 people, 30.77%
Arrhythmias (irregular heartbeat): 7 people, 26.92%
Hypoaesthesia (reduced sense of touch or sensation): 7 people, 26.92%
Pain In Extremity: 7 people, 26.92%
Headache (pain in head): 7 people, 26.92%
Joint Swelling: 6 people, 23.08%
Neuropathy Peripheral (surface nerve damage): 6 people, 23.08%
Feeling Abnormal: 5 people, 19.23%
Gait Disturbance: 5 people, 19.23%
Fatigue (feeling of tiredness): 5 people, 19.23%

What are the existing conditions these people have? *

Endometrial Cancer: 4 people, 15.38%
Adenocarcinoma (malignant tumour formed from glandular structures in epithelial tissue): 3 people, 11.54%
Birth Control: 2 people, 7.69%
Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 2 people, 7.69%
Depression: 2 people, 7.69%
Ovarian Cancer (cancer of ovary): 2 people, 7.69%
Stress And Anxiety: 2 people, 7.69%
Lung Cancer - Non-Small Cell (lung cancer): 2 people, 7.69%
Endometrial Cancer Stage Iii: 1 person, 3.85%
Breast Cancer Metastatic: 1 person, 3.85%

* Approximation only. Some reports may have incomplete information.

Do you take Paclitaxel and have Restless leg syndrome?

- Check whether Restless leg syndrome is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Paclitaxel:

Paclitaxel (85,928 reports)

Browse all side effects of Paclitaxel:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Restless leg syndrome:

Restless leg syndrome (1,245 drugs)

Browse all the conditions that are associated with Restless leg syndrome:

Restless leg syndrome (1,933 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on paclitaxel (the active ingredients of Paclitaxel) and Paclitaxel (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.