Pantoprazole and Bone marrow toxicity - a phase IV clinical study of FDA data

Summary:

Bone marrow toxicity is reported as a side effect among people who take Pantoprazole (pantoprazole sodium), especially for people who are male, 50-59 old, also take Acetylsalicylic Acid, and have Non-hodgkin's lymphoma.

The phase IV clinical study analyzes which people have Bone marrow toxicity when taking Pantoprazole. It is created by eHealthMe based on reports of 281,696 people who have side effects when taking Pantoprazole from the FDA, and is updated regularly.

What is Pantoprazole?

Pantoprazole has active ingredients of pantoprazole sodium. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 285,167 Pantoprazole users. Check the latest studies of Pantoprazole.

What is Bone marrow toxicity?

Bone marrow toxicity (decrease in cells responsible for providing immunity, carrying oxygen, and those responsible for normal blood clotting) is found to be associated with 171 drugs and 376 conditions by eHealthMe. Check the latest studies of Bone marrow toxicity.

On Aug, 11, 2026

281,696 people reported to have side effects when taking Pantoprazole.
Among them, 51 people (0.02%) have Bone marrow toxicity.

Could Pantoprazole cause Bone marrow toxicity?

Among these 51 people:

What is the gender of people who have Bone marrow toxicity when taking Pantoprazole? *

female: 26 %
male: 74 %

What is the age of people who have Bone marrow toxicity when taking Pantoprazole? *

What are other drugs people take besides Pantoprazole? *

What are other side effects people have besides Bone marrow toxicity? *

Anaemia (lack of blood): 33 people, 64.71%
Acute Myocardial Infarction (acute heart attack): 28 people, 54.90%
Chronic Kidney Disease: 28 people, 54.90%
Angina Unstable (chest pain due to ischemia of the heart muscle- unstable): 28 people, 54.90%
Deep Venous Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 28 people, 54.90%
Osteoporosis (bones weak and more likely to break): 28 people, 54.90%
Lymph Follicular Hypertrophy (an increase in the size of the lymph node follicles): 28 people, 54.90%
Post Procedural Haemorrhage (post procedural bleeding): 28 people, 54.90%
Pulmonary Embolism (blockage of the main artery of the lung): 28 people, 54.90%
Drug Resistance (reduction in effectiveness of a drug): 26 people, 50.98%

What are the existing conditions these people have? *

Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 28 people, 54.90%
Roseolovirus Test Positive: 6 people, 11.76%
Depression: 6 people, 11.76%
Lung Consolidation (a condition whereby the lung tissues solidify because of the accumulation of solid and liquid material in the air spaces): 5 people, 9.80%
Encephalitis Viral (inflammation of the brain due to viral infection): 5 people, 9.80%
Fat Embolism (fat obstruction due to injury): 3 people, 5.88%
Psoriasis (immune-mediated disease that affects the skin): 3 people, 5.88%
Human Herpesvirus 6 Infection: 2 people, 3.92%
Graft Versus Host Disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body): 2 people, 3.92%
Acute Lymphocytic Leukemia (All) (cancer of the white blood cells characterized by excess lymphoblasts): 1 person, 1.96%

* Approximation only. Some reports may have incomplete information.

Do you take Pantoprazole and have Bone marrow toxicity?

- Check whether Bone marrow toxicity is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Pantoprazole:

Pantoprazole (285,167 reports)

Browse all side effects of Pantoprazole:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Bone marrow toxicity:

Bone marrow toxicity (171 drugs)

Browse all the conditions that are associated with Bone marrow toxicity:

Bone marrow toxicity (376 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on pantoprazole sodium (the active ingredients of Pantoprazole) and Pantoprazole (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.