Paroxetine and Autoimmune hepatitis - a phase IV clinical study of FDA data

Summary:

Autoimmune hepatitis is reported as a side effect among people who take Paroxetine (paroxetine hydrochloride), especially for people who are female, 50-59 old, have been taking the drug for 1 - 6 months also take Ribavirin, and have Depression.

The phase IV clinical study analyzes which people have Autoimmune hepatitis when taking Paroxetine. It is created by eHealthMe based on reports of 63,800 people who have side effects when taking Paroxetine from the FDA, and is updated regularly.

What is Paroxetine?

Paroxetine has active ingredients of paroxetine hydrochloride. It is often used in stress and anxiety. eHealthMe is studying from 65,088 Paroxetine users. Check the latest studies of Paroxetine.

What is Autoimmune hepatitis?

Autoimmune hepatitis is found to be associated with 588 drugs and 816 conditions by eHealthMe. Check the latest studies of Autoimmune hepatitis.

On Jul, 20, 2026

63,800 people reported to have side effects when taking Paroxetine.
Among them, 23 people (0.04%) have Autoimmune hepatitis.

Could Paroxetine cause Autoimmune hepatitis?

Among these 23 people:

How long have people been on Paroxetine when they have Autoimmune hepatitis? *

What is the gender of people who have Autoimmune hepatitis when taking Paroxetine? *

female: 77.27 %
male: 22.73 %

What is the age of people who have Autoimmune hepatitis when taking Paroxetine? *

What are other drugs people take besides Paroxetine? *

What are other side effects people have besides Autoimmune hepatitis? *

Hepatic Encephalopathy (spectrum of neuropsychiatric abnormalities in patients with liver failure): 6 people, 26.09%
Multi-Organ Failure (multisystem organ failure): 5 people, 21.74%
Sepsis (a severe blood infection that can lead to organ failure and death): 4 people, 17.39%
Cholangitis (infection of the bile duct): 3 people, 13.04%
Joint Pain: 3 people, 13.04%
Hyperventilation: 2 people, 8.70%
Muscle Aches (muscle pain): 2 people, 8.70%
Microalbuminuria (albumin into the urine): 2 people, 8.70%
Liver Function Test Abnormal: 2 people, 8.70%
Diabetes Mellitus Inadequate Control: 2 people, 8.70%

What are the existing conditions these people have? *

Depression: 5 people, 21.74%
Hepatitis C: 3 people, 13.04%
Pain: 2 people, 8.70%
Thrombosis (formation of a blood clot inside a blood vessel): 1 person, 4.35%
Asthma: 1 person, 4.35%
Bone Sarcoma (bone cancer): 1 person, 4.35%
Constipation: 1 person, 4.35%
Coronary Heart Disease (narrowing or blockage of the coronary arteries): 1 person, 4.35%
Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 1 person, 4.35%
Dyslipidaemia (abnormal amount of lipids): 1 person, 4.35%

* Approximation only. Some reports may have incomplete information.

Do you take Paroxetine and have Autoimmune hepatitis?

- Check whether Autoimmune hepatitis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Paroxetine:

Paroxetine (65,088 reports)

Browse all side effects of Paroxetine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Autoimmune hepatitis:

Autoimmune hepatitis (588 drugs)

Browse all the conditions that are associated with Autoimmune hepatitis:

Autoimmune hepatitis (816 conditions)

Related publications that referenced our studies

Coskun M, Adak I, Akaltun I, "Bilateral gynecomastia in a preadolescent boy while under treatment with methylphenidate and paroxetine", Journal of clinical psychopharmacology, 2014 Aug .
Coskun M, Adak I, Akaltun I, "Bilateral gynecomastia in a preadolescent boy while under treatment with methylphenidate and paroxetine", Journal of clinical psychopharmacology, 2014 Aug .

How the study uses the data?

The study uses data from the FDA. It is based on paroxetine hydrochloride (the active ingredients of Paroxetine) and Paroxetine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.