Paroxetine and Hepatocellular injury - a phase IV clinical study of FDA data
Summary:
Hepatocellular injury is reported as a side effect among people who take Paroxetine (paroxetine hydrochloride), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Paracetamol, and have Depression.
The phase IV clinical study analyzes which people have Hepatocellular injury when taking Paroxetine. It is created by eHealthMe based on reports of 63,800 people who have side effects when taking Paroxetine from the FDA, and is updated regularly.
What is Paroxetine?
Paroxetine has active ingredients of paroxetine hydrochloride. It is often used in stress and anxiety. eHealthMe is studying from 65,088 Paroxetine users. Check the latest studies of Paroxetine.
What is Hepatocellular injury?
Hepatocellular injury (liver injury) is found to be associated with 699 drugs and 953 conditions by eHealthMe. Check the latest studies of Hepatocellular injury.
63,800 people reported to have side effects when taking Paroxetine.
Among them, 205 people (0.32%) have Hepatocellular injury.

Among these 205 people:
How long have people been on Paroxetine when they have Hepatocellular injury? *
What is the gender of people who have Hepatocellular injury when taking Paroxetine? *
What is the age of people who have Hepatocellular injury when taking Paroxetine? *
What are other drugs people take besides Paroxetine? *
What are other side effects people have besides Hepatocellular injury? *
What are the existing conditions these people have? *
* Approximation only. Some reports may have incomplete information.
Do you take Paroxetine and have Hepatocellular injury?
- Check whether Hepatocellular injury is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, long term effects of, and alternative drugs to Paroxetine:
- Paroxetine (65,088 reports)
Hepatocellular injury treatments and more:
- Hepatocellular injury (15,445 reports)
How severe was Hepatocellular injury and when was it recovered:
Expand to all the drugs that have ingredients of paroxetine hydrochloride:
Sub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Paroxetine:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all the drugs that are associated with Hepatocellular injury:
- Hepatocellular injury (699 drugs)
Browse all the conditions that are associated with Hepatocellular injury:
- Hepatocellular injury (953 conditions)
Related publications that referenced our studies
- Coskun M, Adak I, Akaltun I, "Bilateral gynecomastia in a preadolescent boy while under treatment with methylphenidate and paroxetine", Journal of clinical psychopharmacology, 2014 Aug .
- Coskun M, Adak I, Akaltun I, "Bilateral gynecomastia in a preadolescent boy while under treatment with methylphenidate and paroxetine", Journal of clinical psychopharmacology, 2014 Aug .
How the study uses the data?
The study uses data from the FDA. It is based on paroxetine hydrochloride (the active ingredients of Paroxetine) and Paroxetine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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