Pennsaid and Drowsiness - a phase IV clinical study of FDA data

Summary:

Drowsiness is reported as a side effect among people who take Pennsaid (diclofenac sodium), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Xyrem, and have Narcolepsy.

The phase IV clinical study analyzes which people have Drowsiness when taking Pennsaid. It is created by eHealthMe based on reports of 2,824 people who have side effects when taking Pennsaid from the FDA, and is updated regularly.

What is Pennsaid?

Pennsaid has active ingredients of diclofenac sodium. eHealthMe is studying from 2,849 Pennsaid users. Check the latest studies of Pennsaid.

What is Drowsiness?

Drowsiness is found to be associated with 2,865 drugs and 4,797 conditions by eHealthMe. Check the latest studies of Drowsiness.

On Jul, 08, 2026

2,824 people reported to have side effects when taking Pennsaid.
Among them, 21 people (0.74%) have Drowsiness.

Among these 21 people:

How long have people been on Pennsaid when they have Drowsiness? *

What is the gender of people who have Drowsiness when taking Pennsaid? *

female: 100 %
male: 0.0 %

What is the age of people who have Drowsiness when taking Pennsaid? *

What are other drugs people take besides Pennsaid? *

What are other side effects people have besides Drowsiness? *

Fatigue (feeling of tiredness): 7 people, 33.33%
Back Pain: 6 people, 28.57%
Pain In Extremity: 6 people, 28.57%
Joint Pain: 6 people, 28.57%
Appetite - Increased (increased appetite is when you want to eat much more often or in larger quantities than your body requires): 5 people, 23.81%
Nausea And Vomiting: 5 people, 23.81%
Diarrhea: 5 people, 23.81%
Nausea (feeling of having an urge to vomit): 5 people, 23.81%
Headache (pain in head): 5 people, 23.81%
Peripheral Swelling: 4 people, 19.05%

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 6 people, 28.57%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 3 people, 14.29%
Joint Pain: 3 people, 14.29%
Cushing's Syndrome (obesity, a rounded face, increased fat): 3 people, 14.29%
Fibromyalgia (a long-term condition which causes pain all over the body): 2 people, 9.52%
Tendonitis (a condition that causes pain and swelling of tendons): 1 person, 4.76%
Flatulence (flatus expelled through the anus): 1 person, 4.76%
Bipolar Disorder (mood disorder): 1 person, 4.76%
Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 1 person, 4.76%
Diarrhea: 1 person, 4.76%

* Approximation only. Some reports may have incomplete information.

Do you take Pennsaid and have Drowsiness?

- Check whether Drowsiness is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Pennsaid:

Pennsaid (2,849 reports)

Drowsiness treatments and more:

Drowsiness (269,040 reports)

Browse all side effects of Pennsaid:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Drowsiness:

Drowsiness (2,865 drugs)

Browse all the conditions that are associated with Drowsiness:

Drowsiness (4,797 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on diclofenac sodium (the active ingredients of Pennsaid) and Pennsaid (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.