Pepcid ac and Anaphylaxis - a phase IV clinical study of FDA data

Summary:

Anaphylaxis is reported as a side effect among people who take Pepcid ac (famotidine), especially for people who are female, 30-39 old, also take Xolair, and have Asthma.

The phase IV clinical study analyzes which people have Anaphylaxis when taking Pepcid ac. It is created by eHealthMe based on reports of 9,299 people who have side effects when taking Pepcid ac from the FDA, and is updated regularly.

What is Pepcid ac?

Pepcid ac has active ingredients of famotidine. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 9,573 Pepcid ac users. Check the latest studies of Pepcid ac.

What is Anaphylaxis?

Anaphylaxis (serious allergic reaction that is rapid in onset and may cause death) is found to be associated with 1,940 drugs and 2,856 conditions by eHealthMe. Check the latest studies of Anaphylaxis.

On Jul, 18, 2026

9,299 people reported to have side effects when taking Pepcid ac.
Among them, 23 people (0.25%) have Anaphylaxis.

Among these 23 people:

What is the gender of people who have Anaphylaxis when taking Pepcid ac? *

female: 90.91 %
male: 9.09 %

What is the age of people who have Anaphylaxis when taking Pepcid ac? *

What are other drugs people take besides Pepcid ac? *

What are other side effects people have besides Anaphylaxis? *

Rashes (redness): 7 people, 30.43%
Stress And Anxiety: 7 people, 30.43%
Dyspnea (difficult or laboured breathing): 6 people, 26.09%
Itching: 6 people, 26.09%
Asthma: 5 people, 21.74%
Wheezing (a high-pitched whistling sound made while you breath): 5 people, 21.74%
Pain: 5 people, 21.74%
Speech Disorder: 4 people, 17.39%
Headache (pain in head): 4 people, 17.39%
Multiple Allergies (allergy to multiple agents): 4 people, 17.39%

What are the existing conditions these people have? *

Asthma: 11 people, 47.83%
Depression: 6 people, 26.09%
Allergic Rhinitis: 5 people, 21.74%
Glucose Tolerance Impaired (blood glucose is raised beyond normal levels, but not high enough to warrant a diabetes diagnosis): 5 people, 21.74%
Attention Deficit Hyperactivity Disorder (a chronic condition including attention difficulty, hyperactivity, and impulsiveness): 5 people, 21.74%
Birth Control: 5 people, 21.74%
Chronic Thyroiditis (long lasting inflammation of thyroid gland): 5 people, 21.74%
Insomnia (sleeplessness): 5 people, 21.74%
Hypersensitivity: 3 people, 13.04%
Urticaria (rash of round, red welts on the skin that itch intensely): 2 people, 8.70%

* Approximation only. Some reports may have incomplete information.

Do you take Pepcid ac and have Anaphylaxis?

- Check whether Anaphylaxis is associated with a drug or a condition
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Pepcid ac:

Pepcid ac (9,573 reports)

Anaphylaxis treatments and more:

Anaphylaxis (91,195 reports)

Browse all side effects of Pepcid ac:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Anaphylaxis:

Anaphylaxis (1,940 drugs)

Browse all the conditions that are associated with Anaphylaxis:

Anaphylaxis (2,856 conditions)

Related publications that referenced our studies

An?eli? N, Erdeljan S, Popovi? R, Bo?i? T, "Anaphylaxis on graft reperfusion during orthotopic liver transplantation: A case study", Srpski arhiv za celokupno lekarstvo, 2016 Jan .
Thangakunam B, Christopher DJ, Mathews V, Srivastava A, "Mesenchymal stromal stem cell therapy in advanced interstitial lung disease-Anaphylaxis and short-term follow-up", Lung India: official organ of Indian Chest Society, 2015 Jan .
Guensley Delva, M. D., & Muse, I, "Rare case of laryngeal edema and anaphylaxis to Ofirmev (IV Acetaminophen): Case Report", , 2012 Jan .
Azkur D, Yoldas T, Toyran M, Kocabas CN, "A pediatric case of anaphylaxis due to octreotide", Asian Pacific journal of allergy and immunology, 2011 Dec .
An?eli? N, Erdeljan S, Popovi? R, Bo?i? T, "Anaphylaxis on graft reperfusion during orthotopic liver transplantation: A case study", Srpski arhiv za celokupno lekarstvo, 2016 Jan .
Thangakunam B, Christopher DJ, Mathews V, Srivastava A, "Mesenchymal stromal stem cell therapy in advanced interstitial lung disease-Anaphylaxis and short-term follow-up", Lung India: official organ of Indian Chest Society, 2015 Jan .
Guensley Delva, M. D., & Muse, I, "Rare case of laryngeal edema and anaphylaxis to Ofirmev (IV Acetaminophen): Case Report", , 2012 Jan .
Azkur D, Yoldas T, Toyran M, Kocabas CN, "A pediatric case of anaphylaxis due to octreotide", Asian Pacific journal of allergy and immunology, 2011 Dec .

How the study uses the data?

The study uses data from the FDA. It is based on famotidine (the active ingredients of Pepcid ac) and Pepcid ac (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.