Pepcid ac and Heart palpitations - a phase IV clinical study of FDA data

Summary:

Heart palpitations is reported as a side effect among people who take Pepcid ac (famotidine), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Prilosec, and have High blood pressure.

The phase IV clinical study analyzes which people have Heart palpitations when taking Pepcid ac. It is created by eHealthMe based on reports of 9,299 people who have side effects when taking Pepcid ac from the FDA, and is updated regularly.

What is Pepcid ac?

Pepcid ac has active ingredients of famotidine. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 9,573 Pepcid ac users. Check the latest studies of Pepcid ac.

What is Heart palpitations?

Heart palpitations (feelings or sensations that your heart is pounding or racing) is found to be associated with 2,437 drugs and 3,638 conditions by eHealthMe. Check the latest studies of Heart palpitations.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 03, 2026

9,299 people reported to have side effects when taking Pepcid ac.
Among them, 96 people (1.03%) have Heart palpitations.

Could Pepcid ac cause Heart palpitations?

Among these 96 people:

How long have people been on Pepcid ac when they have Heart palpitations? *

What is the gender of people who have Heart palpitations when taking Pepcid ac? *

female: 63.33 %
male: 36.67 %

What is the age of people who have Heart palpitations when taking Pepcid ac? *

What are other drugs people take besides Pepcid ac? *

What are other side effects people have besides Heart palpitations? *

Fatigue (feeling of tiredness): 26 people, 27.08%
Dyspnea (difficult or laboured breathing): 26 people, 27.08%
Dizziness: 24 people, 25.00%
Joint Pain: 20 people, 20.83%
Headache (pain in head): 18 people, 18.75%
Back Pain: 16 people, 16.67%
Heart Rate Increased: 16 people, 16.67%
Chest Pain: 16 people, 16.67%
Pain: 16 people, 16.67%
Weakness: 15 people, 15.62%

What are the existing conditions these people have? *

High Blood Pressure: 12 people, 12.50%
Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 8 people, 8.33%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 8 people, 8.33%
Pain: 6 people, 6.25%
Enlarged Prostate: 5 people, 5.21%
Immunodeficiency Common Variable: 5 people, 5.21%
Stress And Anxiety: 4 people, 4.17%
Iron Deficiency Anaemia: 4 people, 4.17%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 3 people, 3.12%
Hypersensitivity: 3 people, 3.12%

* Approximation only. Some reports may have incomplete information.

Do you take Pepcid ac and have Heart palpitations?

- Check whether Heart palpitations is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Pepcid ac:

Pepcid ac (9,573 reports)

Browse all side effects of Pepcid ac:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Heart palpitations:

Heart palpitations (2,437 drugs)

Browse all the conditions that are associated with Heart palpitations:

Heart palpitations (3,638 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on famotidine (the active ingredients of Pepcid ac) and Pepcid ac (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.